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Page 1
NF-κB-dependent airway inflammation triggers systemic insulin resistance.
Cyphert TJ, Morris RT, House LM, Barnes TM, Otero YF, Barham WJ, Hunt RP, Zaynagetdinov R, Yull FE, Blackwell TS, McGuinness OP. Cyphert TJ, et al. Among authors: barnes tm. Am J Physiol Regul Integr Comp Physiol. 2015 Nov 1;309(9):R1144-52. doi: 10.1152/ajpregu.00442.2014. Epub 2015 Sep 16. Am J Physiol Regul Integr Comp Physiol. 2015. PMID: 26377563 Free PMC article.
AMPK directly activates mTORC2 to promote cell survival during acute energetic stress.
Kazyken D, Magnuson B, Bodur C, Acosta-Jaquez HA, Zhang D, Tong X, Barnes TM, Steinl GK, Patterson NE, Altheim CH, Sharma N, Inoki K, Cartee GD, Bridges D, Yin L, Riddle SM, Fingar DC. Kazyken D, et al. Among authors: barnes tm. Sci Signal. 2019 Jun 11;12(585):eaav3249. doi: 10.1126/scisignal.aav3249. Sci Signal. 2019. PMID: 31186373 Free PMC article.
The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists.
Bodur C, Kazyken D, Huang K, Ekim Ustunel B, Siroky KA, Tooley AS, Gonzalez IE, Foley DH, Acosta-Jaquez HA, Barnes TM, Steinl GK, Cho KW, Lumeng CN, Riddle SM, Myers MG Jr, Fingar DC. Bodur C, et al. Among authors: barnes tm. EMBO J. 2018 Jan 4;37(1):19-38. doi: 10.15252/embj.201696164. Epub 2017 Nov 17. EMBO J. 2018. PMID: 29150432 Free PMC article.