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A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions.
Cell Chem Biol. 2023 Dec 21;30(12):1666-1679.e6. doi: 10.1016/j.chembiol.2023.07.018. Epub 2023 Aug 24.
Cell Chem Biol. 2023.
PMID: 37625414
Free article.
A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α.
Crespillo-Casado A, Claes Z, Choy MS, Peti W, Bollen M, Ron D.
Crespillo-Casado A, et al. Among authors: claes z.
J Biol Chem. 2018 May 18;293(20):7766-7776. doi: 10.1074/jbc.RA118.002325. Epub 2018 Apr 4.
J Biol Chem. 2018.
PMID: 29618508
Free PMC article.
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The antibiotic robenidine exhibits guanabenz-like cytoprotective properties by a mechanism independent of protein phosphatase PP1:PPP1R15A.
Claes Z, Jonkhout M, Crespillo-Casado A, Bollen M.
Claes Z, et al.
J Biol Chem. 2019 Sep 6;294(36):13478-13486. doi: 10.1074/jbc.RA119.008857. Epub 2019 Jul 23.
J Biol Chem. 2019.
PMID: 31337709
Free PMC article.
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DNA damage-induced allosteric activation of protein phosphatase PP1:NIPP1 through Src kinase-induced circularization of NIPP1.
Wu D, Van der Hoeven G, Claes Z, Van Eynde A, Bollen M.
Wu D, et al. Among authors: claes z.
FEBS J. 2024 Feb 1. doi: 10.1111/febs.17064. Online ahead of print.
FEBS J. 2024.
PMID: 38303113
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