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A threonyl-tRNA synthetase-mediated translation initiation machinery.
Jeong SJ, Park S, Nguyen LT, Hwang J, Lee EY, Giong HK, Lee JS, Yoon I, Lee JH, Kim JH, Kim HK, Kim D, Yang WS, Kim SY, Lee CY, Yu K, Sonenberg N, Kim MH, Kim S. Jeong SJ, et al. Among authors: kim hk. Nat Commun. 2019 Mar 22;10(1):1357. doi: 10.1038/s41467-019-09086-0. Nat Commun. 2019. PMID: 30902983 Free PMC article.
Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1.
Yoon I, Nam M, Kim HK, Moon HS, Kim S, Jang J, Song JA, Jeong SJ, Kim SB, Cho S, Kim Y, Lee J, Yang WS, Yoo HC, Kim K, Kim MS, Yang A, Cho K, Park HS, Hwang GS, Hwang KY, Han JM, Kim JH, Kim S. Yoon I, et al. Among authors: kim hk. Science. 2020 Jan 10;367(6474):205-210. doi: 10.1126/science.aau2753. Epub 2019 Nov 28. Science. 2020. PMID: 31780625
Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.
Lim S, Cho HY, Kim DG, Roh Y, Son SY, Mushtaq AU, Kim M, Bhattarai D, Sivaraman A, Lee Y, Lee J, Yang WS, Kim HK, Kim MH, Lee K, Jeon YH, Kim S. Lim S, et al. Among authors: kim hk. Nat Chem Biol. 2020 Jan;16(1):31-41. doi: 10.1038/s41589-019-0415-2. Epub 2019 Dec 2. Nat Chem Biol. 2020. PMID: 31792442
Stabilization of Cyclin-Dependent Kinase 4 by Methionyl-tRNA Synthetase in p16INK4a-Negative Cancer.
Kwon NH, Lee JY, Ryu YL, Kim C, Kong J, Oh S, Kang BS, Ahn HW, Ahn SG, Jeong J, Kim HK, Kim JH, Han DY, Park MC, Kim D, Takase R, Masuda I, Hou YM, Jang SI, Chang YS, Lee DK, Kim Y, Wang MW, Basappa, Kim S. Kwon NH, et al. Among authors: kim hk. ACS Pharmacol Transl Sci. 2018 Apr 24;1(1):21-31. doi: 10.1021/acsptsci.8b00001. eCollection 2018 Sep 14. ACS Pharmacol Transl Sci. 2018. PMID: 32219202 Free PMC article.
Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction.
Kim JH, Lee C, Lee M, Wang H, Kim K, Park SJ, Yoon I, Jang J, Zhao H, Kim HK, Kwon NH, Jeong SJ, Yoo HC, Kim JH, Yang JS, Lee MY, Lee CW, Yun J, Oh SJ, Kang JS, Martinis SA, Hwang KY, Guo M, Han G, Han JM, Kim S. Kim JH, et al. Among authors: kim hk. Nat Commun. 2017 Sep 29;8(1):732. doi: 10.1038/s41467-017-00785-0. Nat Commun. 2017. PMID: 28963468 Free PMC article.