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Page 1
Evaluation of the uncertainty of a quantitative approach to drug metabolites in the absence of authentic standards.
Bioanalysis. 2020 Jan;12(1):7-10. doi: 10.4155/bio-2019-0217.
Bioanalysis. 2020.
PMID: 31849265
No abstract available.
Evaluating exposure using confidence intervals: implication in tiered quantitation of metabolites for safety risks.
Niwa M, Ishii T, Ono K, Kuriyama S, Nakai N, Hosaka S, Mayumi T, Yasuda Y, Yamakawa T.
Niwa M, et al. Among authors: nakai n.
Bioanalysis. 2018 Oct;10(19):1553-1556. doi: 10.4155/bio-2018-0217.
Bioanalysis. 2018.
PMID: 30295549
No abstract available.
Item in Clipboard
Giving consideration to scientific validation in Japanese drug application by Japan Bioanalysis Forum discussion group.
Koseki N, Ashizawa H, Ishii T, Uchimura T, Ono K, Kuriyama S, Toda A, Soejima K, Nakai N, Nishimura N, Mayumi T, Yasuda Y, Yamakawa T, Niwa M.
Koseki N, et al. Among authors: nakai n.
Bioanalysis. 2017 Jul;9(13):963-968. doi: 10.4155/bio-2017-0092.
Bioanalysis. 2017.
PMID: 28708436
No abstract available.
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Pharmacokinetic mechanism involved in the prolonged high retention of laninamivir in mouse respiratory tissues after intranasal administration of its prodrug laninamivir octanoate.
Koyama K, Nakai D, Takahashi M, Nakai N, Kobayashi N, Imai T, Izumi T.
Koyama K, et al. Among authors: nakai n.
Drug Metab Dispos. 2013 Jan;41(1):180-7. doi: 10.1124/dmd.112.048280. Epub 2012 Oct 22.
Drug Metab Dispos. 2013.
PMID: 23091189
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CS-8958, a prodrug of the novel neuraminidase inhibitor R-125489, demonstrates a favorable long-retention profile in the mouse respiratory tract.
Koyama K, Takahashi M, Oitate M, Nakai N, Takakusa H, Miura S, Okazaki O.
Koyama K, et al. Among authors: nakai n.
Antimicrob Agents Chemother. 2009 Nov;53(11):4845-51. doi: 10.1128/AAC.00731-09. Epub 2009 Aug 17.
Antimicrob Agents Chemother. 2009.
PMID: 19687241
Free PMC article.
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