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Year Number of Results
2013 1
2014 3
2015 3
2016 1
2018 1
2019 6
2020 4
2022 3
2023 7
2024 2

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29 results

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Page 1
Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways.
Basile G, Vetere A, Hu J, Ijaduola O, Zhang Y, Liu KC, Eltony AM, De Jesus DF, Fukuda K, Doherty G, Leech CA, Chepurny OG, Holz GG, Yun SH, Andersson O, Choudhary A, Wagner BK, Kulkarni RN. Basile G, et al. Among authors: de jesus df. Cell Metab. 2023 Jul 11;35(7):1242-1260.e9. doi: 10.1016/j.cmet.2023.05.007. Epub 2023 Jun 19. Cell Metab. 2023. PMID: 37339634 Free PMC article.
Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b.
Patel SJ, Liu N, Piaker S, Gulko A, Andrade ML, Heyward FD, Sermersheim T, Edinger N, Srinivasan H, Emont MP, Westcott GP, Luther J, Chung RT, Yan S, Kumari M, Thomas R, Deleye Y, Tchernof A, White PJ, Baselli GA, Meroni M, De Jesus DF, Ahmad R, Kulkarni RN, Valenti L, Tsai L, Rosen ED. Patel SJ, et al. Among authors: de jesus df. Sci Transl Med. 2022 Mar 23;14(637):eabh3831. doi: 10.1126/scitranslmed.abh3831. Epub 2022 Mar 23. Sci Transl Med. 2022. PMID: 35320000 Free PMC article.
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes.
F De Jesus D, Zhang Z, Brown NK, Li X, Xiao L, Hu J, Gaffrey MJ, Fogarty G, Kahraman S, Wei J, Basile G, Rana TM, Mathews C, Powers AC, Parent AV, Atkinson MA, Dhe-Paganon S, Eizirik DL, Qian WJ, He C, Kulkarni RN. F De Jesus D, et al. Nat Cell Biol. 2024 Mar;26(3):421-437. doi: 10.1038/s41556-024-01368-0. Epub 2024 Feb 26. Nat Cell Biol. 2024. PMID: 38409327 Free PMC article.
Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.
Wang X, Li Y, Qiang G, Wang K, Dai J, McCann M, Munoz MD, Gil V, Yu Y, Li S, Yang Z, Xu S, Cordoba-Chacon J, De Jesus DF, Sun B, Chen K, Wang Y, Liu X, Miao Q, Zhou L, Hu R, Ding Q, Kulkarni RN, Gao D, Blüher M, Liew CW. Wang X, et al. Among authors: de jesus df. Nat Commun. 2022 Nov 28;13(1):7323. doi: 10.1038/s41467-022-34259-9. Nat Commun. 2022. PMID: 36443308 Free PMC article.
E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance.
Shirakawa J, Togashi Y, Basile G, Okuyama T, Inoue R, Fernandez M, Kyohara M, De Jesus DF, Goto N, Zhang W, Tsuno T, Kin T, Pan H, Dreyfuss JM, Shapiro AMJ, Yi P, Terauchi Y, Kulkarni RN. Shirakawa J, et al. Among authors: de jesus df. Cell Rep. 2022 Oct 4;41(1):111436. doi: 10.1016/j.celrep.2022.111436. Cell Rep. 2022. PMID: 36198264 Free PMC article.
Epigenetic modifiers of islet function and mass.
De Jesus DF, Kulkarni RN. De Jesus DF, et al. Trends Endocrinol Metab. 2014 Dec;25(12):628-36. doi: 10.1016/j.tem.2014.08.006. Epub 2014 Sep 19. Trends Endocrinol Metab. 2014. PMID: 25246382 Review.
m 6 A mRNA Methylation Regulates Early Pancreatic β-Cell Differentiation.
Kahraman S, De Jesus DF, Wei J, Brown NK, Zou Z, Hu J, He C, Kulkarni RN. Kahraman S, et al. Among authors: de jesus df. bioRxiv [Preprint]. 2023 Aug 3:2023.08.03.551675. doi: 10.1101/2023.08.03.551675. bioRxiv. 2023. PMID: 37577492 Free PMC article. Preprint.
29 results