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2006 1
2008 1
2009 1
2011 2
2012 1
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2015 3
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2018 2
2019 2
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2024 1

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15 results

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Page 1
Extended exposure to low doses of azacitidine induces differentiation of leukemic stem cells through activation of myeloperoxidase.
Jeyaraju DV, Alapa M, Polonskaia A, Risueño A, Subramanyam P, Anand A, Ghosh K, Kyriakopoulos C, Hemerich D, Hurren R, Wang X, Gronda M, Ahsan A, Chiu H, Thomas G, Lind EF, Menezes DL, Schimmer AD, Hagner PR, Gandhi A, Thakurta AG. Jeyaraju DV, et al. Haematologica. 2024 Apr 1;109(4):1082-1094. doi: 10.3324/haematol.2023.283437. Haematologica. 2024. PMID: 37941406 Free PMC article.
Mitochondrial carrier homolog 2 is necessary for AML survival.
Khan DH, Mullokandov M, Wu Y, Voisin V, Gronda M, Hurren R, Wang X, MacLean N, Jeyaraju DV, Jitkova Y, Xu GW, Laister R, Seneviratne A, Blatman ZM, Ketela T, Bader GD, Marhon SA, De Carvalho DD, Minden MD, Gross A, Schimmer AD. Khan DH, et al. Among authors: jeyaraju dv. Blood. 2020 Jul 2;136(1):81-92. doi: 10.1182/blood.2019000106. Blood. 2020. PMID: 32299104 Free article.
Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal.
Singh RP, Jeyaraju DV, Voisin V, Hurren R, Xu C, Hawley JR, Barghout SH, Khan DH, Gronda M, Wang X, Jitkova Y, Sharon D, Liyanagae S, MacLean N, Seneviratene AK, Mirali S, Borenstein A, Thomas GE, Soriano J, Orouji E, Minden MD, Arruda A, Chan SM, Bader GD, Lupien M, Schimmer AD. Singh RP, et al. Among authors: jeyaraju dv. Cell Stem Cell. 2020 Jun 4;26(6):926-937.e10. doi: 10.1016/j.stem.2020.04.010. Epub 2020 May 15. Cell Stem Cell. 2020. PMID: 32416059 Free article.
Calcium regulation of mitochondria motility and morphology.
Jeyaraju DV, Cisbani G, Pellegrini L. Jeyaraju DV, et al. Biochim Biophys Acta. 2009 Nov;1787(11):1363-73. doi: 10.1016/j.bbabio.2008.12.005. Epub 2008 Dec 24. Biochim Biophys Acta. 2009. PMID: 19138660 Free article. Review.
Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemia.
Barghout SH, Patel PS, Wang X, Xu GW, Kavanagh S, Halgas O, Zarabi SF, Gronda M, Hurren R, Jeyaraju DV, MacLean N, Brennan S, Hyer ML, Berger A, Traore T, Milhollen M, Smith AC, Minden MD, Pai EF, Hakem R, Schimmer AD. Barghout SH, et al. Among authors: jeyaraju dv. Leukemia. 2019 Jan;33(1):37-51. doi: 10.1038/s41375-018-0167-0. Epub 2018 Jun 8. Leukemia. 2019. PMID: 29884901
Mitochondrial DNA damage by bleomycin induces AML cell death.
Yeung M, Hurren R, Nemr C, Wang X, Hershenfeld S, Gronda M, Liyanage S, Wu Y, Augustine J, Lee EA, Spagnuolo PA, Southall N, Chen C, Zheng W, Jeyaraju DV, Minden MD, Laposa R, Schimmer AD. Yeung M, et al. Among authors: jeyaraju dv. Apoptosis. 2015 Jun;20(6):811-20. doi: 10.1007/s10495-015-1119-z. Apoptosis. 2015. PMID: 25820141
Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia.
Cole A, Wang Z, Coyaud E, Voisin V, Gronda M, Jitkova Y, Mattson R, Hurren R, Babovic S, Maclean N, Restall I, Wang X, Jeyaraju DV, Sukhai MA, Prabha S, Bashir S, Ramakrishnan A, Leung E, Qia YH, Zhang N, Combes KR, Ketela T, Lin F, Houry WA, Aman A, Al-Awar R, Zheng W, Wienholds E, Xu CJ, Dick J, Wang JC, Moffat J, Minden MD, Eaves CJ, Bader GD, Hao Z, Kornblau SM, Raught B, Schimmer AD. Cole A, et al. Among authors: jeyaraju dv. Cancer Cell. 2015 Jun 8;27(6):864-76. doi: 10.1016/j.ccell.2015.05.004. Cancer Cell. 2015. PMID: 26058080 Free PMC article.
The thymidine dideoxynucleoside analog, alovudine, inhibits the mitochondrial DNA polymerase γ, impairs oxidative phosphorylation and promotes monocytic differentiation in acute myeloid leukemia.
Yehudai D, Liyanage SU, Hurren R, Rizoska B, Albertella M, Gronda M, Jeyaraju DV, Wang X, Barghout SH, MacLean N, Siriwardena TP, Jitkova Y, Targett-Adams P, Schimmer AD. Yehudai D, et al. Among authors: jeyaraju dv. Haematologica. 2019 May;104(5):963-972. doi: 10.3324/haematol.2018.195172. Epub 2018 Dec 20. Haematologica. 2019. PMID: 30573504 Free PMC article.
15 results