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Page 1
Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders.
Autophagy. 2022 Feb;18(2):423-442. doi: 10.1080/15548627.2021.1936777. Epub 2021 Jul 21.
Autophagy. 2022.
PMID: 34286667
Free PMC article.
Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks.
Mossink B, van Rhijn JR, Wang S, Linda K, Vitale MR, Zöller JEM, van Hugte EJH, Bak J, Verboven AHA, Selten M, Negwer M, Latour BL, van der Werf I, Keller JM, Klein Gunnewiek TM, Schoenmaker C, Oudakker A, Anania A, Jansen S, Lesch KP, Frega M, van Bokhoven H, Schubert D, Nadif Kasri N.
Mossink B, et al. Among authors: klein gunnewiek tm.
Mol Psychiatry. 2022 Jan;27(1):1-18. doi: 10.1038/s41380-021-01117-x. Epub 2021 May 10.
Mol Psychiatry. 2022.
PMID: 33972691
Free PMC article.
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Sonlicromanol improves neuronal network dysfunction and transcriptome changes linked to m.3243A>G heteroplasmy in iPSC-derived neurons.
Klein Gunnewiek TM, Verboven AHA, Pelgrim I, Hogeweg M, Schoenmaker C, Renkema H, Beyrath J, Smeitink J, de Vries BBA, Hoen PAC', Kozicz T, Nadif Kasri N.
Klein Gunnewiek TM, et al.
Stem Cell Reports. 2021 Sep 14;16(9):2197-2212. doi: 10.1016/j.stemcr.2021.07.002. Epub 2021 Jul 29.
Stem Cell Reports. 2021.
PMID: 34329596
Free PMC article.
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Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro.
Mossink B, Verboven AHA, van Hugte EJH, Klein Gunnewiek TM, Parodi G, Linda K, Schoenmaker C, Kleefstra T, Kozicz T, van Bokhoven H, Schubert D, Nadif Kasri N, Frega M.
Mossink B, et al. Among authors: klein gunnewiek tm.
Stem Cell Reports. 2021 Sep 14;16(9):2182-2196. doi: 10.1016/j.stemcr.2021.07.001. Epub 2021 Jul 29.
Stem Cell Reports. 2021.
PMID: 34329594
Free PMC article.
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m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity.
Klein Gunnewiek TM, Van Hugte EJH, Frega M, Guardia GS, Foreman K, Panneman D, Mossink B, Linda K, Keller JM, Schubert D, Cassiman D, Rodenburg R, Vidal Folch N, Oglesbee D, Perales-Clemente E, Nelson TJ, Morava E, Nadif Kasri N, Kozicz T.
Klein Gunnewiek TM, et al.
Cell Rep. 2020 Apr 21;31(3):107538. doi: 10.1016/j.celrep.2020.107538.
Cell Rep. 2020.
PMID: 32320658
Free article.
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