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Page 1
Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.
Cell Rep Med. 2022 Nov 15;3(11):100815. doi: 10.1016/j.xcrm.2022.100815.
Cell Rep Med. 2022.
PMID: 36384095
Free PMC article.
The Role of Autophagy in Pancreatic Cancer: From Bench to the Dark Bedside.
Görgülü K, Diakopoulos KN, Kaya-Aksoy E, Ciecielski KJ, Ai J, Lesina M, Algül H.
Görgülü K, et al. Among authors: kaya aksoy e.
Cells. 2020 Apr 24;9(4):1063. doi: 10.3390/cells9041063.
Cells. 2020.
PMID: 32344698
Free PMC article.
Review.
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Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
Ruess DA, Heynen GJ, Ciecielski KJ, Ai J, Berninger A, Kabacaoglu D, Görgülü K, Dantes Z, Wörmann SM, Diakopoulos KN, Karpathaki AF, Kowalska M, Kaya-Aksoy E, Song L, van der Laan EAZ, López-Alberca MP, Nazaré M, Reichert M, Saur D, Erkan MM, Hopt UT, Sainz B Jr, Birchmeier W, Schmid RM, Lesina M, Algül H.
Ruess DA, et al. Among authors: kaya aksoy e.
Nat Med. 2018 Jul;24(7):954-960. doi: 10.1038/s41591-018-0024-8. Epub 2018 May 28.
Nat Med. 2018.
PMID: 29808009
Free article.
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The pro-apoptotic Bcl-2 family member Harakiri (HRK) induces cell death in glioblastoma multiforme.
Kaya-Aksoy E, Cingoz A, Senbabaoglu F, Seker F, Sur-Erdem I, Kayabolen A, Lokumcu T, Sahin GN, Karahuseyinoglu S, Bagci-Onder T.
Kaya-Aksoy E, et al.
Cell Death Discov. 2019 Feb 8;5:64. doi: 10.1038/s41420-019-0144-z. eCollection 2019.
Cell Death Discov. 2019.
PMID: 30774992
Free PMC article.
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Bcl3 Couples Cancer Stem Cell Enrichment With Pancreatic Cancer Molecular Subtypes.
Ai J, Wörmann SM, Görgülü K, Vallespinos M, Zagorac S, Alcala S, Wu N, Kabacaoglu D, Berninger A, Navarro D, Kaya-Aksoy E, Ruess DA, Ciecielski KJ, Kowalska M, Demir IE, Ceyhan GO, Heid I, Braren R, Riemann M, Schreiner S, Hofmann S, Kutschke M, Jastroch M, Slotta-Huspenina J, Muckenhuber A, Schlitter AM, Schmid RM, Steiger K, Diakopoulos KN, Lesina M, Sainz B Jr, Algül H.
Ai J, et al. Among authors: kaya aksoy e.
Gastroenterology. 2021 Jul;161(1):318-332.e9. doi: 10.1053/j.gastro.2021.03.051. Epub 2021 Apr 2.
Gastroenterology. 2021.
PMID: 33819482
Free article.
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Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice.
Görgülü K, Diakopoulos KN, Ai J, Schoeps B, Kabacaoglu D, Karpathaki AF, Ciecielski KJ, Kaya-Aksoy E, Ruess DA, Berninger A, Kowalska M, Stevanovic M, Wörmann SM, Wartmann T, Zhao Y, Halangk W, Voronina S, Tepikin A, Schlitter AM, Steiger K, Artati A, Adamski J, Aichler M, Walch A, Jastroch M, Hartleben G, Mantzoros CS, Weichert W, Schmid RM, Herzig S, Krüger A, Sainz B Jr, Lesina M, Algül H.
Görgülü K, et al. Among authors: kaya aksoy e.
Gastroenterology. 2019 Jan;156(1):203-217.e20. doi: 10.1053/j.gastro.2018.09.053. Epub 2018 Oct 6.
Gastroenterology. 2019.
PMID: 30296435
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