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Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21.
Pena-Leon V, Folgueira C, Barja-Fernández S, Pérez-Lois R, Da Silva Lima N, Martin M, Heras V, Martinez-Martinez S, Valero P, Iglesias C, Duquenne M, Al-Massadi O, Beiroa D, Souto Y, Fidalgo M, Sowmyalakshmi R, Guallar D, Cunarro J, Castelao C, Senra A, González-Saenz P, Vázquez-Cobela R, Leis R, Sabio G, Mueller-Fielitz H, Schwaninger M, López M, Tovar S, Casanueva FF, Valjent E, Diéguez C, Prevot V, Nogueiras R, Seoane LM. Pena-Leon V, et al. Among authors: souto y. Nat Metab. 2022 Jul;4(7):901-917. doi: 10.1038/s42255-022-00602-z. Epub 2022 Jul 25. Nat Metab. 2022. PMID: 35879461 Free PMC article.
Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma.
Wang X, Kutschat AP, Aggrey-Fynn J, Hamdan FH, Graham RP, Wixom AQ, Souto Y, Ladigan-Badura S, Yonkus JA, Abdelrahman AM, Alva-Ruiz R, Gaedcke J, Ströbel P, Kosinsky RL, Wegwitz F, Hermann P, Truty MJ, Siveke JT, Hahn SA, Hessmann E, Johnsen SA, Najafova Z. Wang X, et al. Among authors: souto y. Mol Cancer Res. 2023 Sep 1;21(9):881-891. doi: 10.1158/1541-7786.MCR-22-0916. Mol Cancer Res. 2023. PMID: 37279184 Free PMC article.
Inhibition of hepatic p63 ameliorates steatohepatitis with fibrosis in mice.
Fondevila MF, Novoa E, Fernandez U, Dorta V, Parracho T, Kreimeyer H, Garcia-Vence M, Chantada-Vazquez MP, Bravo SB, Porteiro B, Cabaleiro A, Koning M, Senra A, Souto Y, Verheij J, Guallar D, Fidalgo M, Meijnikman AS, da Silva Lima N, Dieguez C, Gonzalez-Rellan MJ, Nogueiras R. Fondevila MF, et al. Among authors: souto y. Mol Metab. 2024 May 28;85:101962. doi: 10.1016/j.molmet.2024.101962. Online ahead of print. Mol Metab. 2024. PMID: 38815625 Free article.
ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress.
Guallar D, Fuentes-Iglesias A, Souto Y, Ameneiro C, Freire-Agulleiro O, Pardavila JA, Escudero A, Garcia-Outeiral V, Moreira T, Saenz C, Xiong H, Liu D, Xiao S, Hou Y, Wu K, Torrecilla D, Hartner JC, Blanco MG, Lee LJ, López M, Walkley CR, Wang J, Fidalgo M. Guallar D, et al. Among authors: souto y. Cell Stem Cell. 2020 Aug 6;27(2):300-314.e11. doi: 10.1016/j.stem.2020.04.016. Epub 2020 May 11. Cell Stem Cell. 2020. PMID: 32396862 Free PMC article.
MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance.
Al-Massadi O, Quiñones M, Clasadonte J, Hernandez-Bautista R, Romero-Picó A, Folgueira C, Morgan DA, Kalló I, Heras V, Senra A, Funderburk SC, Krashes MJ, Souto Y, Fidalgo M, Luquet S, Chee MJ, Imbernon M, Beiroa D, García-Caballero L, Gallego R, Lam BYH, Yeo G, Lopez M, Liposits Z, Rahmouni K, Prevot V, Dieguez C, Nogueiras R. Al-Massadi O, et al. Among authors: souto y. Diabetes. 2019 Dec;68(12):2210-2222. doi: 10.2337/db19-0029. Epub 2019 Sep 16. Diabetes. 2019. PMID: 31530579 Free PMC article.