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ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells.
Cell Commun Signal. 2019 Aug 23;17(1):106. doi: 10.1186/s12964-019-0413-8.
Cell Commun Signal. 2019.
PMID: 31443721
Free PMC article.
Biasing human epidermal growth factor receptor 4 (HER4) tyrosine kinase signaling with antibodies: Induction of cell death by antibody-dependent HER4 intracellular domain trafficking.
Lanotte R, Garambois V, Gaborit N, Larbouret C, Musnier A, Martineau P, Pèlegrin A, Chardès T.
Lanotte R, et al.
Cancer Sci. 2020 Jul;111(7):2508-2525. doi: 10.1111/cas.14458. Epub 2020 Jun 8.
Cancer Sci. 2020.
PMID: 32415868
Free PMC article.
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