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Page 1
Kupffer cells facilitate the acute effects of leptin on hepatic lipid metabolism.
Metlakunta A, Huang W, Stefanovic-Racic M, Dedousis N, Sipula I, O'Doherty RM. Metlakunta A, et al. Among authors: dedousis n. Am J Physiol Endocrinol Metab. 2017 Jan 1;312(1):E11-E18. doi: 10.1152/ajpendo.00250.2016. Epub 2016 Nov 8. Am J Physiol Endocrinol Metab. 2017. PMID: 27827807 Free PMC article.
Hepatocyte-derived GDF15 suppresses feeding and improves insulin sensitivity in obese mice.
Xie B, Murali A, Vandevender AM, Chen J, Silva AG, Bello FM, Chuan B, Bahudhanapati H, Sipula I, Dedousis N, Shah FA, O'Donnell CP, Alder JK, Jurczak MJ. Xie B, et al. Among authors: dedousis n. iScience. 2022 Nov 12;25(12):105569. doi: 10.1016/j.isci.2022.105569. eCollection 2022 Dec 22. iScience. 2022. PMID: 36465107 Free PMC article.
Hepatocyte-Specific Ablation or Whole-Body Inhibition of Xanthine Oxidoreductase in Mice Corrects Obesity-Induced Systemic Hyperuricemia Without Improving Metabolic Abnormalities.
Harmon DB, Mandler WK, Sipula IJ, Dedousis N, Lewis SE, Eckels JT, Du J, Wang Y, Huckestein BR, Pagano PJ, Cifuentes-Pagano E, Homanics GE, Van't Erve TJ, Stefanovic-Racic M, Jurczak MJ, O'Doherty RM, Kelley EE. Harmon DB, et al. Among authors: dedousis n. Diabetes. 2019 Jun;68(6):1221-1229. doi: 10.2337/db18-1198. Epub 2019 Apr 1. Diabetes. 2019. PMID: 30936145 Free PMC article.
Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance.
Belmonte FR, Dedousis N, Sipula I, Desai NA, Singhi AD, Chu Y, Zhang Y, Bannwarth S, Paquis-Flucklinger V, Harrington L, Shiva S, Jurczak MJ, O'Doherty RM, Kaufman BA. Belmonte FR, et al. Among authors: dedousis n. PLoS One. 2019 May 28;14(5):e0203101. doi: 10.1371/journal.pone.0203101. eCollection 2019. PLoS One. 2019. PMID: 31136580 Free PMC article.
Adipose tissue-derived free fatty acids initiate myeloid cell accumulation in mouse liver in states of lipid oversupply.
Harmon DB, Wu C, Dedousis N, Sipula IJ, Stefanovic-Racic M, Schoiswohl G, O'Donnell CP, Alonso LC, Kershaw EE, Kelley EE, O'Doherty RM. Harmon DB, et al. Among authors: dedousis n. Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E758-E770. doi: 10.1152/ajpendo.00172.2018. Epub 2018 Aug 7. Am J Physiol Endocrinol Metab. 2018. PMID: 30086648 Free PMC article.
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