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Page 1
Did you mean g xiao[Author] (10,366 results)?
Mitochondrial Dysfunction and Therapeutic Perspectives in Cardiovascular Diseases.
Liu Y, Huang Y, Xu C, An P, Luo Y, Jiao L, Luo J, Li Y. Liu Y, et al. Among authors: jiao l. Int J Mol Sci. 2022 Dec 16;23(24):16053. doi: 10.3390/ijms232416053. Int J Mol Sci. 2022. PMID: 36555691 Free PMC article. Review.
Furthermore, we explored current potential therapeutic strategies for CVDs by eliminating mtDNA mutations (e.g., mtDNA editing and mitochondrial replacement), enhancing mitophagy, improving OXPHOS capacity (e.g., supplement with NAD(+), nicotinamide riboside (NR), n …
Furthermore, we explored current potential therapeutic strategies for CVDs by eliminating mtDNA mutations (e.g., mtDNA editing and mi …
A method for structure determination of GPCRs in various states.
Guo Q, He B, Zhong Y, Jiao H, Ren Y, Wang Q, Ge Q, Gao Y, Liu X, Du Y, Hu H, Tao Y. Guo Q, et al. Among authors: jiao h. Nat Chem Biol. 2024 Jan;20(1):74-82. doi: 10.1038/s41589-023-01389-0. Epub 2023 Aug 14. Nat Chem Biol. 2024. PMID: 37580554
G-protein-coupled receptors (GPCRs) are a class of integral membrane proteins that detect environmental cues and trigger cellular responses. ...
G-protein-coupled receptors (GPCRs) are a class of integral membrane proteins that detect environmental cues and trigger cellular res …
Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Wang JL, Dou XD, Cheng J, Gao MX, Xu GF, Ding W, Ding JH, Li Y, Wang SH, Ji ZW, Zhao XY, Huo TY, Zhang CF, Liu YM, Sha XY, Gao JR, Zhang WH, Hao Y, Zhang C, Sun JP, Jiao N, Yu X. Wang JL, et al. Among authors: jiao n. Nat Metab. 2023 Oct;5(10):1726-1746. doi: 10.1038/s42255-023-00899-4. Epub 2023 Sep 28. Nat Metab. 2023. PMID: 37770763
By systematically profiling intra-islet lipid-transmembrane receptor signalling in islet-resident macrophages, we identified endogenous 9(S)-hydroxy-10,12-octadecadienoic acid-G-protein-coupled receptor 132 (GPR132)-Gi signalling as a significant contributor to islet macro …
By systematically profiling intra-islet lipid-transmembrane receptor signalling in islet-resident macrophages, we identified endogenous 9(S) …
Mutational analysis of ATP7B in Chinese Wilson disease patients.
Hua R, Hua F, Jiao Y, Pan Y, Yang X, Peng S, Niu J. Hua R, et al. Among authors: jiao y. Am J Transl Res. 2016 Jun 15;8(6):2851-61. eCollection 2016. Am J Transl Res. 2016. PMID: 27398169 Free PMC article.
The results suggested that 66 of the 68 patents carried with at least one mutation and 48 different mutations were identified including 34 missense, one synonymous, two nonsense, two splicing, and nine frameshift mutations (five insertion and four deletion). Among these mutations …
The results suggested that 66 of the 68 patents carried with at least one mutation and 48 different mutations were identified including 34 m …
Activation of G-protein-coupled receptor 183 initiates inflammatory pain via macrophage CCL22 secretion.
Qi Z, Zhong W, Jiao B, Chen K, Yang X, Wang L, Zeng W, Huang J, Xie J. Qi Z, et al. Among authors: jiao b. Eur J Pharmacol. 2023 Sep 5;954:175872. doi: 10.1016/j.ejphar.2023.175872. Epub 2023 Jun 21. Eur J Pharmacol. 2023. PMID: 37353188
Chronic pain is a major public health problem with limited effective therapeutic options. G-protein-coupled receptors play a significant role in pain modulation; however, whether and how G-protein-coupled receptor 183 participates in pain regulation remain unclear. …
Chronic pain is a major public health problem with limited effective therapeutic options. G-protein-coupled receptors play a signific …
Glucose signaling, AtRGS1 and plant autophagy.
Jiao Y, Lei W, Xu W, Chen WL. Jiao Y, et al. Plant Signal Behav. 2019;14(7):1607465. doi: 10.1080/15592324.2019.1607465. Epub 2019 May 6. Plant Signal Behav. 2019. PMID: 31055999 Free PMC article. Review.
It is also a key signaling molecule involved in regulation of many physiologic processes, including organism morphogenesis, anabolism and catabolism, pest and disease stress, environmental stress response. The signal transduction pathway mediated by heterotrimeric G protei …
It is also a key signaling molecule involved in regulation of many physiologic processes, including organism morphogenesis, anabolism and ca …
The Role of G Protein-coupled Receptor Kinases in Cancer.
Yu S, Sun L, Jiao Y, Lee LTO. Yu S, et al. Among authors: jiao y. Int J Biol Sci. 2018 Feb 5;14(2):189-203. doi: 10.7150/ijbs.22896. eCollection 2018. Int J Biol Sci. 2018. PMID: 29483837 Free PMC article. Review.
G protein-coupled receptors (GPCRs) are the largest family of plasma membrane receptors. ...Therefore, development of GPCR-targeted drugs could provide a new therapeutic strategy to treating a variety of cancers. G protein-coupled receptor kinases (GRKs) modulate GP …
G protein-coupled receptors (GPCRs) are the largest family of plasma membrane receptors. ...Therefore, development of GPCR-targeted d …
A Tissue-Like Soft All-Hydrogel Battery.
Ye T, Wang J, Jiao Y, Li L, He E, Wang L, Li Y, Yun Y, Li D, Lu J, Chen H, Li Q, Li F, Gao R, Peng H, Zhang Y. Ye T, et al. Among authors: jiao y. Adv Mater. 2022 Jan;34(4):e2105120. doi: 10.1002/adma.202105120. Epub 2021 Dec 9. Adv Mater. 2022. PMID: 34713511
However, the batteries available cannot reach the softness of tissues due to the high Young's moduli of components (e.g., metals, carbon materials, conductive polymers, or composite materials). ...The ultrasoft batteries exhibit Young's moduli of 80 kPa, perfectly matching …
However, the batteries available cannot reach the softness of tissues due to the high Young's moduli of components (e.g., metals, car …
Mechanism of agonist-induced activation of the human itch receptor MRGPRX1.
Gan B, Yu L, Yang H, Jiao H, Pang B, Chen Y, Wang C, Lv R, Hu H, Cao Z, Ren R. Gan B, et al. Among authors: jiao h. PLoS Biol. 2023 Jun 22;21(6):e3001975. doi: 10.1371/journal.pbio.3001975. eCollection 2023 Jun. PLoS Biol. 2023. PMID: 37347749 Free PMC article.
Mas-related G-protein-coupled receptors X1-X4 (MRGPRX1-X4) are 4 primate-specific receptors that are recently reported to be responsible for many biological processes, including itch sensation, pain transmission, and inflammatory reactions. ...
Mas-related G-protein-coupled receptors X1-X4 (MRGPRX1-X4) are 4 primate-specific receptors that are recently reported to be responsi …
Carbohydrate-based Clostridium difficile vaccines.
Monteiro MA, Ma Z, Bertolo L, Jiao Y, Arroyo L, Hodgins D, Mallozzi M, Vedantam G, Sagermann M, Sundsmo J, Chow H. Monteiro MA, et al. Among authors: jiao y. Expert Rev Vaccines. 2013 Apr;12(4):421-31. doi: 10.1586/erv.13.9. Expert Rev Vaccines. 2013. PMID: 23560922 Review.
2,434 results