Sheryl M Gough[Author] - Search Results

Year	Number of Results
2003	1
2006	1
2011	1
2012	1
2013	1
2014	3
2017	2
2020	1
2024	1

1

NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights.

Gough SM, Slape CI, Aplan PD. Gough SM, et al. Blood. 2011 Dec 8;118(24):6247-57. doi: 10.1182/blood-2011-07-328880. Epub 2011 Sep 26. Blood. 2011. PMID: 21948299 Free PMC article. Review.

2

Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion.

Zhang Y, Guo Y, Gough SM, Zhang J, Vann KR, Li K, Cai L, Shi X, Aplan PD, Wang GG, Kutateladze TG. Zhang Y, et al. Among authors: gough sm. Nat Commun. 2020 Jul 3;11(1):3339. doi: 10.1038/s41467-020-17098-4. Nat Commun. 2020. PMID: 32620764 Free PMC article.

3

Age-related epigenetic drift in the pathogenesis of MDS and AML.

Maegawa S, Gough SM, Watanabe-Okochi N, Lu Y, Zhang N, Castoro RJ, Estecio MR, Jelinek J, Liang S, Kitamura T, Aplan PD, Issa JP. Maegawa S, et al. Among authors: gough sm. Genome Res. 2014 Apr;24(4):580-91. doi: 10.1101/gr.157529.113. Epub 2014 Jan 10. Genome Res. 2014. PMID: 24414704 Free PMC article.

4

Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance.

Goldberg L, Gough SM, Lee F, Dang C, Walker RL, Zhu YJ, Bilke S, Pineda M, Onozawa M, Jo Chung Y, Meltzer PS, Aplan PD. Goldberg L, et al. Among authors: gough sm. Genes Chromosomes Cancer. 2017 Jun;56(6):472-483. doi: 10.1002/gcc.22451. Epub 2017 Mar 31. Genes Chromosomes Cancer. 2017. PMID: 28196408 Free PMC article.

5

Oxidative stress leads to increased mutation frequency in a murine model of myelodysplastic syndrome.

Chung YJ, Robert C, Gough SM, Rassool FV, Aplan PD. Chung YJ, et al. Among authors: gough sm. Leuk Res. 2014 Jan;38(1):95-102. doi: 10.1016/j.leukres.2013.07.008. Epub 2013 Aug 16. Leuk Res. 2014. PMID: 23958061 Free PMC article.

6

Progenitor B-1 B-cell acute lymphoblastic leukemia is associated with collaborative mutations in 3 critical pathways.

Gough SM, Goldberg L, Pineda M, Walker RL, Zhu YJ, Bilke S, Chung YJ, Dufraine J, Kundu S, Jacoby E, Fry TJ, Fischer S, Panzer-Grümayer R, Meltzer PS, Aplan PD. Gough SM, et al. Blood Adv. 2017 Sep 8;1(20):1749-1759. doi: 10.1182/bloodadvances.2017009837. eCollection 2017 Sep 12. Blood Adv. 2017. PMID: 29296821 Free PMC article.

7

Oral estrogen receptor PROTAC® vepdegestrant (ARV-471) is highly efficacious as monotherapy and in combination with CDK4/6 or PI3K/mTOR pathway inhibitors in preclinical ER+ breast cancer models.

Gough SM, Flanagan JJ, Teh J, Andreoli M, Rousseau E, Pannone M, Bookbinder M, Willard R, Davenport K, Bortolon E, Cadelina G, Gordon D, Pizzano J, Macaluso J, Soto L, Corradi J, Digianantonio K, Drulyte I, Morgan A, Quinn C, Békés M, Ferraro C, Chen X, Wang G, Dong H, Wang J, Langley DR, Houston J, Gedrich R, Taylor IC. Gough SM, et al. Clin Cancer Res. 2024 May 31. doi: 10.1158/1078-0432.CCR-23-3465. Online ahead of print. Clin Cancer Res. 2024. PMID: 38819400

8

NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function.

Gough SM, Lee F, Yang F, Walker RL, Zhu YJ, Pineda M, Onozawa M, Chung YJ, Bilke S, Wagner EK, Denu JM, Ning Y, Xu B, Wang GG, Meltzer PS, Aplan PD. Gough SM, et al. Cancer Discov. 2014 May;4(5):564-77. doi: 10.1158/2159-8290.CD-13-0419. Epub 2014 Feb 17. Cancer Discov. 2014. PMID: 24535671 Free PMC article.

9

Depletion of cytotoxic T-cells does not protect NUP98-HOXD13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect.

Gough SM, Chung YJ, Aplan PD. Gough SM, et al. PLoS One. 2012;7(5):e36876. doi: 10.1371/journal.pone.0036876. Epub 2012 May 11. PLoS One. 2012. PMID: 22606303 Free PMC article.

10

Refined physical map of the human PAX2/HOX11/NFKB2 cancer gene region at 10q24 and relocalization of the HPV6AI1 viral integration site to 14q13.3-q21.1.

Gough SM, McDonald M, Chen XN, Korenberg JR, Neri A, Kahn T, Eccles MR, Morris CM. Gough SM, et al. BMC Genomics. 2003 Mar 3;4(1):9. doi: 10.1186/1471-2164-4-9. Epub 2003 Mar 3. BMC Genomics. 2003. PMID: 12697057 Free PMC article.

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