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PAF1 regulation of promoter-proximal pause release via enhancer activation.
Chen FX, Xie P, Collings CK, Cao K, Aoi Y, Marshall SA, Rendleman EJ, Ugarenko M, Ozark PA, Zhang A, Shiekhattar R, Smith ER, Zhang MQ, Shilatifard A. Chen FX, et al. Among authors: ugarenko m. Science. 2017 Sep 22;357(6357):1294-1298. doi: 10.1126/science.aan3269. Epub 2017 Aug 31. Science. 2017. PMID: 28860207 Free PMC article.
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation.
Douillet D, Sze CC, Ryan C, Piunti A, Shah AP, Ugarenko M, Marshall SA, Rendleman EJ, Zha D, Helmin KA, Zhao Z, Cao K, Morgan MA, Singer BD, Bartom ET, Smith ER, Shilatifard A. Douillet D, et al. Among authors: ugarenko m. Nat Genet. 2020 Jun;52(6):615-625. doi: 10.1038/s41588-020-0618-1. Epub 2020 May 11. Nat Genet. 2020. PMID: 32393859 Free PMC article.
CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.
Piunti A, Smith ER, Morgan MAJ, Ugarenko M, Khaltyan N, Helmin KA, Ryan CA, Murray DC, Rickels RA, Yilmaz BD, Rendleman EJ, Savas JN, Singer BD, Bulun SE, Shilatifard A. Piunti A, et al. Among authors: ugarenko m. Sci Adv. 2019 Jul 3;5(7):eaax2887. doi: 10.1126/sciadv.aax2887. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31281901 Free PMC article.