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Pharmacologic IRE1/XBP1s activation promotes systemic adaptive remodeling in obesity.
Nat Commun. 2022 Feb 1;13(1):608. doi: 10.1038/s41467-022-28271-2.
Nat Commun. 2022.
PMID: 35105890
Free PMC article.
Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming.
Grandjean JMD, Madhavan A, Cech L, Seguinot BO, Paxman RJ, Smith E, Scampavia L, Powers ET, Cooley CB, Plate L, Spicer TP, Kelly JW, Wiseman RL.
Grandjean JMD, et al. Among authors: madhavan a.
Nat Chem Biol. 2020 Oct;16(10):1052-1061. doi: 10.1038/s41589-020-0584-z. Epub 2020 Jul 20.
Nat Chem Biol. 2020.
PMID: 32690944
Free PMC article.
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PERK signaling promotes mitochondrial elongation by remodeling membrane phosphatidic acid.
Perea V, Cole C, Lebeau J, Dolina V, Baron KR, Madhavan A, Kelly JW, Grotjahn DA, Wiseman RL.
Perea V, et al. Among authors: madhavan a.
EMBO J. 2023 Aug 1;42(15):e113908. doi: 10.15252/embj.2023113908. Epub 2023 Jun 12.
EMBO J. 2023.
PMID: 37306086
Free PMC article.
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The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress.
Lebeau J, Saunders JM, Moraes VWR, Madhavan A, Madrazo N, Anthony MC, Wiseman RL.
Lebeau J, et al. Among authors: madhavan a.
Cell Rep. 2018 Mar 13;22(11):2827-2836. doi: 10.1016/j.celrep.2018.02.055.
Cell Rep. 2018.
PMID: 29539413
Free PMC article.
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