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Year Number of Results
2017 1
2018 2
2019 4
2020 5
2021 4
2022 5
2023 3
2024 0

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22 results

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Page 1
TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome.
Olsen RHJ, DiBerto JF, English JG, Glaudin AM, Krumm BE, Slocum ST, Che T, Gavin AC, McCorvy JD, Roth BL, Strachan RT. Olsen RHJ, et al. Among authors: slocum st. Nat Chem Biol. 2020 Aug;16(8):841-849. doi: 10.1038/s41589-020-0535-8. Epub 2020 May 4. Nat Chem Biol. 2020. PMID: 32367019 Free PMC article.
Structure, function and pharmacology of human itch GPCRs.
Cao C, Kang HJ, Singh I, Chen H, Zhang C, Ye W, Hayes BW, Liu J, Gumpper RH, Bender BJ, Slocum ST, Krumm BE, Lansu K, McCorvy JD, Kroeze WK, English JG, DiBerto JF, Olsen RHJ, Huang XP, Zhang S, Liu Y, Kim K, Karpiak J, Jan LY, Abraham SN, Jin J, Shoichet BK, Fay JF, Roth BL. Cao C, et al. Among authors: slocum st. Nature. 2021 Dec;600(7887):170-175. doi: 10.1038/s41586-021-04126-6. Epub 2021 Nov 17. Nature. 2021. PMID: 34789874 Free PMC article.
Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys.
Nagai Y, Miyakawa N, Takuwa H, Hori Y, Oyama K, Ji B, Takahashi M, Huang XP, Slocum ST, DiBerto JF, Xiong Y, Urushihata T, Hirabayashi T, Fujimoto A, Mimura K, English JG, Liu J, Inoue KI, Kumata K, Seki C, Ono M, Shimojo M, Zhang MR, Tomita Y, Nakahara J, Suhara T, Takada M, Higuchi M, Jin J, Roth BL, Minamimoto T. Nagai Y, et al. Among authors: slocum st. Nat Neurosci. 2020 Sep;23(9):1157-1167. doi: 10.1038/s41593-020-0661-3. Epub 2020 Jul 6. Nat Neurosci. 2020. PMID: 32632286
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity.
Kaplan AL, Confair DN, Kim K, Barros-Álvarez X, Rodriguiz RM, Yang Y, Kweon OS, Che T, McCorvy JD, Kamber DN, Phelan JP, Martins LC, Pogorelov VM, DiBerto JF, Slocum ST, Huang XP, Kumar JM, Robertson MJ, Panova O, Seven AB, Wetsel AQ, Wetsel WC, Irwin JJ, Skiniotis G, Shoichet BK, Roth BL, Ellman JA. Kaplan AL, et al. Among authors: slocum st. Nature. 2022 Oct;610(7932):582-591. doi: 10.1038/s41586-022-05258-z. Epub 2022 Sep 28. Nature. 2022. PMID: 36171289 Free PMC article.
Structure-based design of bitopic ligands for the µ-opioid receptor.
Faouzi A, Wang H, Zaidi SA, DiBerto JF, Che T, Qu Q, Robertson MJ, Madasu MK, El Daibani A, Varga BR, Zhang T, Ruiz C, Liu S, Xu J, Appourchaux K, Slocum ST, Eans SO, Cameron MD, Al-Hasani R, Pan YX, Roth BL, McLaughlin JP, Skiniotis G, Katritch V, Kobilka BK, Majumdar S. Faouzi A, et al. Among authors: slocum st. Nature. 2023 Jan;613(7945):767-774. doi: 10.1038/s41586-022-05588-y. Epub 2022 Nov 30. Nature. 2023. PMID: 36450356 Free PMC article.
Molecular insights into psychedelic drug action.
Slocum ST, DiBerto JF, Roth BL. Slocum ST, et al. J Neurochem. 2022 Jul;162(1):24-38. doi: 10.1111/jnc.15540. Epub 2021 Dec 1. J Neurochem. 2022. PMID: 34797943 Free article. Review.
Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator.
Krumm BE, DiBerto JF, Olsen RHJ, Kang HJ, Slocum ST, Zhang S, Strachan RT, Huang XP, Slosky LM, Pinkerton AB, Barak LS, Caron MG, Kenakin T, Fay JF, Roth BL. Krumm BE, et al. Among authors: slocum st. Biochemistry. 2023 Apr 4;62(7):1233-1248. doi: 10.1021/acs.biochem.3c00029. Epub 2023 Mar 14. Biochemistry. 2023. PMID: 36917754
Oxidative Metabolism as a Modulator of Kratom's Biological Actions.
Chakraborty S, Uprety R, Slocum ST, Irie T, Le Rouzic V, Li X, Wilson LL, Scouller B, Alder AF, Kruegel AC, Ansonoff M, Varadi A, Eans SO, Hunkele A, Allaoa A, Kalra S, Xu J, Pan YX, Pintar J, Kivell BM, Pasternak GW, Cameron MD, McLaughlin JP, Sames D, Majumdar S. Chakraborty S, et al. Among authors: slocum st. J Med Chem. 2021 Nov 25;64(22):16553-16572. doi: 10.1021/acs.jmedchem.1c01111. Epub 2021 Nov 16. J Med Chem. 2021. PMID: 34783240 Free PMC article.
Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor.
Levit Kaplan A, Strachan RT, Braz JM, Craik V, Slocum S, Mangano T, Amabo V, O'Donnell H, Lak P, Basbaum AI, Roth BL, Shoichet BK. Levit Kaplan A, et al. Among authors: slocum s. J Med Chem. 2022 Mar 10;65(5):4201-4217. doi: 10.1021/acs.jmedchem.1c02031. Epub 2022 Feb 23. J Med Chem. 2022. PMID: 35195401 Free PMC article.
22 results