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Functionally Integrated Top-Down Proteomics for Standardized Assessment of Human Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues.
Melby JA, de Lange WJ, Zhang J, Roberts DS, Mitchell SD, Tucholski T, Kim G, Kyrvasilis A, McIlwain SJ, Kamp TJ, Ralphe JC, Ge Y. Melby JA, et al. Among authors: mitchell sd. J Proteome Res. 2021 Feb 5;20(2):1424-1433. doi: 10.1021/acs.jproteome.0c00830. Epub 2021 Jan 4. J Proteome Res. 2021. PMID: 33395532 Free PMC article.
Analysis of cardiac troponin proteoforms by top-down mass spectrometry.
Tiambeng TN, Tucholski T, Wu Z, Zhu Y, Mitchell SD, Roberts DS, Jin Y, Ge Y. Tiambeng TN, et al. Among authors: mitchell sd. Methods Enzymol. 2019;626:347-374. doi: 10.1016/bs.mie.2019.07.029. Epub 2019 Aug 27. Methods Enzymol. 2019. PMID: 31606082 Free PMC article.
Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics.
Tucholski T, Cai W, Gregorich ZR, Bayne EF, Mitchell SD, McIlwain SJ, de Lange WJ, Wrobbel M, Karp H, Hite Z, Vikhorev PG, Marston SB, Lal S, Li A, Dos Remedios C, Kohmoto T, Hermsen J, Ralphe JC, Kamp TJ, Moss RL, Ge Y. Tucholski T, et al. Among authors: mitchell sd. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24691-24700. doi: 10.1073/pnas.2006764117. Epub 2020 Sep 23. Proc Natl Acad Sci U S A. 2020. PMID: 32968017 Free PMC article.