Jinshan Nan[Author] - Search Results

Year	Number of Results
2020	3
2022	3
2023	5
2024	2

1

A new generation M^pro inhibitor with potent activity against SARS-CoV-2 Omicron variants.

Huang C, Shuai H, Qiao J, Hou Y, Zeng R, Xia A, Xie L, Fang Z, Li Y, Yoon C, Huang Q, Hu B, You J, Quan B, Zhao X, Guo N, Zhang S, Ma R, Zhang J, Wang Y, Yang R, Zhang S, Nan J, Xu H, Wang F, Lei J, Chu H, Yang S. Huang C, et al. Among authors: nan j. Signal Transduct Target Ther. 2023 Mar 16;8(1):128. doi: 10.1038/s41392-023-01392-w. Signal Transduct Target Ther. 2023. PMID: 36928316 Free PMC article.

2

Targeting Noncanonical Pyroptosis With a Small Molecular Inhibitor Alleviates Inflammation in the LPS-Induced Keratitis Mouse Model.

Zhang Y, Zhou N, Jiao Y, Lin G, Li X, Gao S, Zhou P, Liu J, Nan J, Zhang M, Yang S. Zhang Y, et al. Among authors: nan j. Invest Ophthalmol Vis Sci. 2023 Jan 3;64(1):1. doi: 10.1167/iovs.64.1.1. Invest Ophthalmol Vis Sci. 2023. PMID: 36595275 Free PMC article.

3

Discovery of a novel pyroptosis inhibitor acting though modulating glutathionylation to suppress NLRP3-related signal pathway.

Zhou N, Zhang Y, Jiao Y, Nan J, Xia A, Mu B, Lin G, Li X, Zhang S, Yang S, Li L. Zhou N, et al. Among authors: nan j. Int Immunopharmacol. 2024 Jan 25;127:111314. doi: 10.1016/j.intimp.2023.111314. Epub 2023 Dec 10. Int Immunopharmacol. 2024. PMID: 38081102

4

Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants.

Pan S, Zhang L, Luo X, Nan J, Yang W, Bin H, Li Y, Huang Q, Wang T, Pan Z, Mu B, Wang F, Tian C, Liu Y, Li L, Yang S. Pan S, et al. Among authors: nan j. J Med Chem. 2022 Feb 10;65(3):2035-2058. doi: 10.1021/acs.jmedchem.1c01597. Epub 2022 Jan 26. J Med Chem. 2022. PMID: 35080890

5

Discovery of thieno[2,3-d]pyrimidin-4(3H)-one derivatives as a new class of ROCK inhibitors.

Miao Z, Sun YM, Zhao LY, Li YS, Wang YF, Nan JS, Qiao ZE, Li LL, Yang SY. Miao Z, et al. Bioorg Med Chem Lett. 2020 Mar 15;30(6):126966. doi: 10.1016/j.bmcl.2020.126966. Epub 2020 Jan 15. Bioorg Med Chem Lett. 2020. PMID: 32001136

6

Discovery of small molecule FLT3 inhibitors that are able to overcome drug-resistant mutations.

Zhang G, Zhang W, Shen C, Nan J, Chen M, Lai S, Zhong J, Li B, Wang T, Wang Y, Yang S, Li L. Zhang G, et al. Among authors: nan j. Bioorg Med Chem Lett. 2020 Nov 15;30(22):127532. doi: 10.1016/j.bmcl.2020.127532. Epub 2020 Sep 3. Bioorg Med Chem Lett. 2020. PMID: 32891702

7

Discovery of (S)-3-(4-(benzyloxy)phenyl)-2-(2-phenoxyacetamido)propanoic acid derivatives as a new class of GPR34 antagonists.

Zhou P, Zhao J, Hu Q, Lin G, Zhang J, Xia A, Zhang S, Nan J, Li L. Zhou P, et al. Among authors: nan j. Bioorg Med Chem Lett. 2024 Jan 1;97:129548. doi: 10.1016/j.bmcl.2023.129548. Epub 2023 Nov 9. Bioorg Med Chem Lett. 2024. PMID: 37949379

8

Discovery of 4-(1,2,4-Oxadiazol-5-yl)azepan-2-one Derivatives as a New Class of Cannabinoid Type 2 Receptor Agonists for the Treatment of Inflammatory Pain.

Nan J, Liu J, Lin G, Zhang S, Xia A, Zhou P, Zhou Y, Zhang J, Zhao J, Zhang S, Huang C, Wang Y, Hu Q, Chen J, Xiang M, Yang X, Yang S. Nan J, et al. J Med Chem. 2023 Mar 9;66(5):3460-3483. doi: 10.1021/acs.jmedchem.2c01943. Epub 2023 Feb 23. J Med Chem. 2023. PMID: 36821347

9

Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis.

Jiao Y, Nan J, Mu B, Zhang Y, Zhou N, Yang S, Zhang S, Lin W, Wang F, Xia A, Cao Z, Chen P, Pan Z, Lin G, Pan S, Bin H, Li L, Yang S. Jiao Y, et al. Among authors: nan j. Eur J Med Chem. 2022 Mar 15;232:114194. doi: 10.1016/j.ejmech.2022.114194. Epub 2022 Feb 11. Eur J Med Chem. 2022. PMID: 35183871

10

Discovery of a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3-Related (ATR) kinase: Structural activity relationship and antitumor activity both in vitro and in vivo.

Bin H, Chen P, Wu M, Wang F, Lin G, Pan S, Liu J, Mu B, Nan J, Huang Q, Li L, Yang S. Bin H, et al. Among authors: nan j. Eur J Med Chem. 2022 Mar 15;232:114187. doi: 10.1016/j.ejmech.2022.114187. Epub 2022 Feb 12. Eur J Med Chem. 2022. PMID: 35183872

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