Accelarated immune ageing is associated with COVID-19 disease severity.
Lord JM, Veenith T, Sullivan J, Sharma-Oates A, Richter AG, Greening NJ, McAuley HJC, Evans RA, Moss P, Moore SC, Turtle L, Gautam N, Gilani A, Bajaj M, Wain LV, Brightling C, Raman B, Marks M, Singapuri A, Elneima O, Openshaw PJM, Duggal NA; PHOSP-COVID Study collaborative group; ISARIC4C investigators.
Lord JM, et al. Among authors: gautam n.
Immun Ageing. 2024 Jan 11;21(1):6. doi: 10.1186/s12979-023-00406-z.
Immun Ageing. 2024.
PMID: 38212801
Free PMC article.
We found increased immunesenescence features in severe COVID-19 survivors compared to controls including: a reduced frequency and number of naive CD4 and CD8 T cells (p < 0.0001); increased frequency of EMRA CD4 (p < 0.003) and CD8 T cells (p < 0.001
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We found increased immunesenescence features in severe COVID-19 survivors compared to controls including: a reduced frequency and number of …