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The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial.
Schwenzer H, De Zan E, Elshani M, van Stiphout R, Kudsy M, Morris J, Ferrari V, Um IH, Chettle J, Kazmi F, Campo L, Easton A, Nijman S, Serpi M, Symeonides S, Plummer R, Harrison DJ, Bond G, Blagden SP. Schwenzer H, et al. Among authors: de zan e. Clin Cancer Res. 2021 Dec 1;27(23):6500-6513. doi: 10.1158/1078-0432.CCR-21-1652. Epub 2021 Sep 8. Clin Cancer Res. 2021. PMID: 34497073 Free PMC article.
The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation.
Kulicke CA, De Zan E, Hein Z, Gonzalez-Lopez C, Ghanwat S, Veerapen N, Besra GS, Klenerman P, Christianson JC, Springer S, Nijman SM, Cerundolo V, Salio M. Kulicke CA, et al. Among authors: de zan e. J Biol Chem. 2022 Feb;298(2):101542. doi: 10.1016/j.jbc.2021.101542. Epub 2021 Dec 27. J Biol Chem. 2022. PMID: 34968463 Free PMC article.
Targeting hepatocyte growth factor receptor (Met) positive tumor cells using internalizing nanobody-decorated albumin nanoparticles.
Heukers R, Altintas I, Raghoenath S, De Zan E, Pepermans R, Roovers RC, Haselberg R, Hennink WE, Schiffelers RM, Kok RJ, van Bergen en Henegouwen PM. Heukers R, et al. Among authors: de zan e. Biomaterials. 2014 Jan;35(1):601-10. doi: 10.1016/j.biomaterials.2013.10.001. Epub 2013 Oct 16. Biomaterials. 2014. PMID: 24139763 Free article.
Dual Role For A MEK Inhibitor As A Modulator Of Inflammation And Host Defense Mechanisms With Potential Therapeutic Application In COPD.
Kurian N, Cohen TS, Öberg L, De Zan E, Skogberg G, Vollmer S, Baturcam E, Svanberg P, Bonn B, Smith PD, Vaarala O, Cunoosamy DM. Kurian N, et al. Among authors: de zan e. Int J Chron Obstruct Pulmon Dis. 2019 Nov 26;14:2611-2624. doi: 10.2147/COPD.S211619. eCollection 2019. Int J Chron Obstruct Pulmon Dis. 2019. PMID: 32063702 Free PMC article.