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Page 1
Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma.
Frias A, Di Leo L, Antoranz A, Nazerai L, Carretta M, Bodemeyer V, Pagliuca C, Dahl C, Claps G, Mandelli GE, Andhari MD, Pacheco MP, Sauter T, Robert C, Guldberg P, Madsen DH, Cecconi F, Bosisio FM, De Zio D. Frias A, et al. J Immunother Cancer. 2023 Mar;11(3):e006389. doi: 10.1136/jitc-2022-006389. J Immunother Cancer. 2023. PMID: 36868570 Free PMC article.
Loss of Ambra1 promotes melanoma growth and invasion.
Di Leo L, Bodemeyer V, Bosisio FM, Claps G, Carretta M, Rizza S, Faienza F, Frias A, Khan S, Bordi M, Pacheco MP, Di Martino J, Bravo-Cordero JJ, Daniel CJ, Sears RC, Donia M, Madsen DH, Guldberg P, Filomeni G, Sauter T, Robert C, De Zio D, Cecconi F. Di Leo L, et al. Among authors: frias a. Nat Commun. 2021 May 5;12(1):2550. doi: 10.1038/s41467-021-22772-2. Nat Commun. 2021. PMID: 33953176 Free PMC article.
Thiopurine 6TG treatment increases tumor immunogenicity and response to immune checkpoint blockade.
Nazerai L, Willis SC, Yankilevich P, Di Leo L, Bosisio FM, Frias A, Bertolotto C, Nersting J, Thastrup M, Buus S, Thomsen AR, Nielsen M, Rohrberg KS, Schmiegelow K, De Zio D. Nazerai L, et al. Among authors: frias a. Oncoimmunology. 2022 Dec 17;12(1):2158610. doi: 10.1080/2162402X.2022.2158610. eCollection 2023. Oncoimmunology. 2022. PMID: 36545256 Free PMC article.
SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells.
Obara EAA, Aguilar-Morante D, Rasmussen RD, Frias A, Vitting-Serup K, Lim YC, Elbæk KJ, Pedersen H, Vardouli L, Jensen KE, Skjoth-Rasmussen J, Brennum J, Tuckova L, Strauss R, Dinant C, Bartek J, Hamerlik P. Obara EAA, et al. Among authors: frias a. Nat Commun. 2020 Sep 18;11(1):4709. doi: 10.1038/s41467-020-18549-8. Nat Commun. 2020. PMID: 32948765 Free PMC article.
Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability.
Viñas-Castells R, Frías Á, Robles-Lanuza E, Zhang K, Longmore GD, García de Herreros A, Díaz VM. Viñas-Castells R, et al. Among authors: frias a. Nucleic Acids Res. 2014 Jan;42(2):1079-94. doi: 10.1093/nar/gkt935. Epub 2013 Oct 23. Nucleic Acids Res. 2014. PMID: 24157836 Free PMC article.
Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-smallcell Lung Cancer Associated With Poor Prognosis.
Karachaliou N, Chaib I, Cardona AF, Berenguer J, Bracht JWP, Yang J, Cai X, Wang Z, Hu C, Drozdowskyj A, Servat CC, Servat JC, Ito M, Attili I, Aldeguer E, Capitan AG, Rodriguez J, Rojas L, Viteri S, Molina-Vila MA, Ou SI, Okada M, Mok TS, Bivona TG, Ono M, Cui J, Ramón Y Cajal S, Frias A, Cao P, Rosell R. Karachaliou N, et al. Among authors: frias a. EBioMedicine. 2018 Mar;29:112-127. doi: 10.1016/j.ebiom.2018.02.001. Epub 2018 Feb 5. EBioMedicine. 2018. PMID: 29433983 Free PMC article.