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Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans.
Galletti G, De Simone G, Mazza EMC, Puccio S, Mezzanotte C, Bi TM, Davydov AN, Metsger M, Scamardella E, Alvisi G, De Paoli F, Zanon V, Scarpa A, Camisa B, Colombo FS, Anselmo A, Peano C, Polletti S, Mavilio D, Gattinoni L, Boi SK, Youngblood BA, Jones RE, Baird DM, Gostick E, Llewellyn-Lacey S, Ladell K, Price DA, Chudakov DM, Newell EW, Casucci M, Lugli E. Galletti G, et al. Among authors: scamardella e. Nat Immunol. 2020 Dec;21(12):1552-1562. doi: 10.1038/s41590-020-0791-5. Epub 2020 Oct 12. Nat Immunol. 2020. PMID: 33046887 Free PMC article.
Antioxidant metabolism regulates CD8+ T memory stem cell formation and antitumor immunity.
Pilipow K, Scamardella E, Puccio S, Gautam S, De Paoli F, Mazza EM, De Simone G, Polletti S, Buccilli M, Zanon V, Di Lucia P, Iannacone M, Gattinoni L, Lugli E. Pilipow K, et al. Among authors: scamardella e. JCI Insight. 2018 Sep 20;3(18):e122299. doi: 10.1172/jci.insight.122299. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232291 Free PMC article.
CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential.
De Simone G, Mazza EMC, Cassotta A, Davydov AN, Kuka M, Zanon V, De Paoli F, Scamardella E, Metsger M, Roberto A, Pilipow K, Colombo FS, Tenedini E, Tagliafico E, Gattinoni L, Mavilio D, Peano C, Price DA, Singh SP, Farber JM, Serra V, Cucca F, Ferrari F, Orrù V, Fiorillo E, Iannacone M, Chudakov DM, Sallusto F, Lugli E. De Simone G, et al. Among authors: scamardella e. J Immunol. 2019 Dec 15;203(12):3179-3189. doi: 10.4049/jimmunol.1901072. Epub 2019 Nov 18. J Immunol. 2019. PMID: 31740485 Free PMC article.
Curtailed T-cell activation curbs effector differentiation and generates CD8+ T cells with a naturally-occurring memory stem cell phenotype.
Zanon V, Pilipow K, Scamardella E, De Paoli F, De Simone G, Price DA, Martinez Usatorre A, Romero P, Mavilio D, Roberto A, Lugli E. Zanon V, et al. Among authors: scamardella e. Eur J Immunol. 2017 Sep;47(9):1468-1476. doi: 10.1002/eji.201646732. Epub 2017 Jul 28. Eur J Immunol. 2017. PMID: 28671275 Free PMC article.