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Page 1
NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis.
Cell Commun Signal. 2021 Sep 22;19(1):96. doi: 10.1186/s12964-021-00776-1.
Cell Commun Signal. 2021.
PMID: 34551776
Free PMC article.
A novel chemical attack on Notch-mediated transcription by targeting the NACK ATPase.
Diluvio G, Kelley TT, Lahiry M, Alvarez-Trotta A, Kolb EM, Shersher E, Astudillo L, Kovall RA, Schürer SC, Capobianco AJ.
Diluvio G, et al.
Mol Ther Oncolytics. 2023 Feb 22;28:307-320. doi: 10.1016/j.omto.2023.02.008. eCollection 2023 Mar 16.
Mol Ther Oncolytics. 2023.
PMID: 36938545
Free PMC article.
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Pharmacological Disruption of the Notch1 Transcriptional Complex Inhibits Tumor Growth by Selectively Targeting Cancer Stem Cells.
Alvarez-Trotta A, Guerrant W, Astudillo L, Lahiry M, Diluvio G, Shersher E, Kaneku H, Robbins DJ, Orton D, Capobianco AJ.
Alvarez-Trotta A, et al. Among authors: diluvio g.
Cancer Res. 2021 Jun 15;81(12):3347-3357. doi: 10.1158/0008-5472.CAN-20-3611. Epub 2021 Apr 5.
Cancer Res. 2021.
PMID: 33820800
Free PMC article.
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Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response.
Giuli MV, Diluvio G, Giuliani E, Franciosa G, Di Magno L, Pignataro MG, Tottone L, Nicoletti C, Besharat ZM, Peruzzi G, Pelullo M, Palermo R, Canettieri G, Talora C, d'Amati G, Bellavia D, Screpanti I, Checquolo S.
Giuli MV, et al. Among authors: diluvio g.
Oncogenesis. 2020 Oct 18;9(10):93. doi: 10.1038/s41389-020-00279-7.
Oncogenesis. 2020.
PMID: 33071287
Free PMC article.
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NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.
Diluvio G, Del Gaudio F, Giuli MV, Franciosa G, Giuliani E, Palermo R, Besharat ZM, Pignataro MG, Vacca A, d'Amati G, Maroder M, Talora C, Capalbo C, Bellavia D, Checquolo S.
Diluvio G, et al.
Oncogenesis. 2018 May 25;7(5):42. doi: 10.1038/s41389-018-0051-9.
Oncogenesis. 2018.
PMID: 29795369
Free PMC article.
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