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Page 1
Site Selective Chlorination of C(sp3 )-H Bonds Suitable for Late-Stage Functionalization.
Angew Chem Int Ed Engl. 2021 Apr 6;60(15):8276-8283. doi: 10.1002/anie.202016548. Epub 2021 Mar 4.
Angew Chem Int Ed Engl. 2021.
PMID: 33480134
Free PMC article.
Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties.
Soth MJ, Le K, Di Francesco ME, Hamilton MM, Liu G, Burke JP, Carroll CL, Kovacs JJ, Bardenhagen JP, Bristow CA, Cardozo M, Czako B, de Stanchina E, Feng N, Garvey JR, Gay JP, Do MKG, Greer J, Han M, Harris A, Herrera Z, Huang S, Giuliani V, Jiang Y, Johnson SB, Johnson TA, Kang Z, Leonard PG, Liu Z, McAfoos T, Miller M, Morlacchi P, Mullinax RA, Palmer WS, Pang J, Rogers N, Rudin CM, Shepard HE, Spencer ND, Theroff J, Wu Q, Xu A, Yau JA, Draetta G, Toniatti C, Heffernan TP, Jones P.
Soth MJ, et al. Among authors: herrera z.
J Med Chem. 2020 Nov 12;63(21):12957-12977. doi: 10.1021/acs.jmedchem.0c01398. Epub 2020 Oct 29.
J Med Chem. 2020.
PMID: 33118821
Free PMC article.
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Specific Inhibition of the Bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase in Malaria Parasites via a New Small-Molecule Binding Site.
Gisselberg JE, Herrera Z, Orchard LM, Llinás M, Yeh E.
Gisselberg JE, et al. Among authors: herrera z.
Cell Chem Biol. 2018 Feb 15;25(2):185-193.e5. doi: 10.1016/j.chembiol.2017.11.010. Epub 2017 Dec 21.
Cell Chem Biol. 2018.
PMID: 29276048
Free PMC article.
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Elevated transglutaminase 2 activity is associated with hypoxia-induced experimental pulmonary hypertension in mice.
DiRaimondo TR, Klöck C, Warburton R, Herrera Z, Penumatsa K, Toksoz D, Hill N, Khosla C, Fanburg B.
DiRaimondo TR, et al. Among authors: herrera z.
ACS Chem Biol. 2014 Jan 17;9(1):266-75. doi: 10.1021/cb4006408. Epub 2013 Nov 5.
ACS Chem Biol. 2014.
PMID: 24152195
Free PMC article.
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Discovery of potent and specific dihydroisoxazole inhibitors of human transglutaminase 2.
Klöck C, Herrera Z, Albertelli M, Khosla C.
Klöck C, et al. Among authors: herrera z.
J Med Chem. 2014 Nov 13;57(21):9042-64. doi: 10.1021/jm501145a. Epub 2014 Oct 31.
J Med Chem. 2014.
PMID: 25333388
Free PMC article.
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A chemical rescue screen identifies a Plasmodium falciparum apicoplast inhibitor targeting MEP isoprenoid precursor biosynthesis.
Wu W, Herrera Z, Ebert D, Baska K, Cho SH, DeRisi JL, Yeh E.
Wu W, et al. Among authors: herrera z.
Antimicrob Agents Chemother. 2015 Jan;59(1):356-64. doi: 10.1128/AAC.03342-14. Epub 2014 Nov 3.
Antimicrob Agents Chemother. 2015.
PMID: 25367906
Free PMC article.
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