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Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers.
Sci Transl Med. 2023 Aug 2;15(707):eadf7006. doi: 10.1126/scitranslmed.adf7006. Epub 2023 Aug 2.
Sci Transl Med. 2023.
PMID: 37531417
Free PMC article.
Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations.
Intlekofer AM, Shih AH, Wang B, Nazir A, Rustenburg AS, Albanese SK, Patel M, Famulare C, Correa FM, Takemoto N, Durani V, Liu H, Taylor J, Farnoud N, Papaemmanuil E, Cross JR, Tallman MS, Arcila ME, Roshal M, Petsko GA, Wu B, Choe S, Konteatis ZD, Biller SA, Chodera JD, Thompson CB, Levine RL, Stein EM.
Intlekofer AM, et al. Among authors: durani v.
Nature. 2018 Jul;559(7712):125-129. doi: 10.1038/s41586-018-0251-7. Epub 2018 Jun 27.
Nature. 2018.
PMID: 29950729
Free PMC article.
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MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer.
Caeser R, Hulton C, Costa E, Durani V, Little M, Chen X, Tischfield SE, Asher M, Kombak FE, Chavan SS, Shah NS, Ciampricotti M, de Stanchina E, Poirier JT, Rudin CM, Sen T.
Caeser R, et al. Among authors: durani v.
iScience. 2021 Oct 5;24(11):103224. doi: 10.1016/j.isci.2021.103224. eCollection 2021 Nov 19.
iScience. 2021.
PMID: 34712921
Free PMC article.
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Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition.
Cai SF, Chu SH, Goldberg AD, Parvin S, Koche RP, Glass JL, Stein EM, Tallman MS, Sen F, Famulare CA, Cusan M, Huang CH, Chen CW, Zou L, Cordner KB, DelGaudio NL, Durani V, Kini M, Rex M, Tian HS, Zuber J, Baslan T, Lowe SW, Rienhoff HY Jr, Letai A, Levine RL, Armstrong SA.
Cai SF, et al. Among authors: durani v.
Cancer Discov. 2020 Oct;10(10):1500-1513. doi: 10.1158/2159-8290.CD-19-1469. Epub 2020 Jun 30.
Cancer Discov. 2020.
PMID: 32606137
Free PMC article.
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A JAK2/IDH1-mutant MPN clone unmasked by ivosidenib in an AML patient without antecedent MPN.
Xiao W, Miles LA, Bowman RL, Durani V, Tian HS, DelGaudio NL, Mishra T, Zhu M, Zhang Y, Stump SE, Tallman MS, Levine RL, Cai SF.
Xiao W, et al. Among authors: durani v.
Blood Adv. 2020 Dec 8;4(23):6034-6038. doi: 10.1182/bloodadvances.2020003326.
Blood Adv. 2020.
PMID: 33284943
Free PMC article.
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