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Did you mean maria rivadeneira[Author] (16 results)?
Safety, Pharmacokinetics, and Pharmacodynamics of Etavopivat (FT-4202), an Allosteric Activator of Pyruvate Kinase-R, in Healthy Adults: A Randomized, Placebo-Controlled, Double-Blind, First-in-Human Phase 1 Trial.
Forsyth S, Schroeder P, Geib J, Vrishabhendra L, Konstantinidis DG, LaSalvia K, Ribadeneira MD, Wu E, Kelly P, Kalfa TA. Forsyth S, et al. Among authors: ribadeneira md. Clin Pharmacol Drug Dev. 2022 May;11(5):654-665. doi: 10.1002/cpdd.1058. Epub 2022 Jan 12. Clin Pharmacol Drug Dev. 2022. PMID: 35019238 Free PMC article. Clinical Trial.
KCNQ channel openers reverse depressive symptoms via an active resilience mechanism.
Friedman AK, Juarez B, Ku SM, Zhang H, Calizo RC, Walsh JJ, Chaudhury D, Zhang S, Hawkins A, Dietz DM, Murrough JW, Ribadeneira M, Wong EH, Neve RL, Han MH. Friedman AK, et al. Among authors: ribadeneira m. Nat Commun. 2016 May 24;7:11671. doi: 10.1038/ncomms11671. Nat Commun. 2016. PMID: 27216573 Free PMC article.
Inhibition of fatty acid synthase with FT-4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non-alcoholic fatty liver disease: Results from two early-phase randomized trials.
Beysen C, Schroeder P, Wu E, Brevard J, Ribadeneira M, Lu W, Dole K, O'Reilly T, Morrow L, Hompesch M, Hellerstein MK, Li K, Johansson L, Kelly PF. Beysen C, et al. Among authors: ribadeneira m. Diabetes Obes Metab. 2021 Mar;23(3):700-710. doi: 10.1111/dom.14272. Epub 2020 Dec 21. Diabetes Obes Metab. 2021. PMID: 33289350 Free PMC article. Clinical Trial.
Development and SAR of functionally selective allosteric modulators of GABAA receptors.
Alhambra C, Becker C, Blake T, Chang AH, Damewood JR Jr, Daniels T, Dembofsky BT, Gurley DA, Hall JE, Herzog KJ, Horchler CL, Ohnmacht CJ, Schmiesing RJ, Dudley A, Ribadeneira MD, Knappenberger KS, Maciag C, Stein MM, Chopra M, Liu XF, Christian EP, Arriza JL, Chapdelaine MJ. Alhambra C, et al. Among authors: ribadeneira md. Bioorg Med Chem. 2011 May 1;19(9):2927-38. doi: 10.1016/j.bmc.2011.03.035. Epub 2011 Mar 29. Bioorg Med Chem. 2011. PMID: 21498079
A strategy to reduce biliary clearance in early drug discovery.
Rioux N, Bellavance E, Poirier H, Dupuis M, Garneau M, Ribadeneira MD, Duan J. Rioux N, et al. Among authors: ribadeneira md. J Pharmacol Toxicol Methods. 2013 Nov-Dec;68(3):346-8. doi: 10.1016/j.vascn.2013.03.003. Epub 2013 Mar 19. J Pharmacol Toxicol Methods. 2013. PMID: 23518065
A new 4-(2-methylquinolin-4-ylmethyl)phenyl P1' group for the beta-amino hydroxamic acid derived TACE inhibitors.
Chen XT, Ghavimi B, Corbett RL, Xue CB, Liu RQ, Covington MB, Qian M, Vaddi KG, Christ DD, Hartman KD, Ribadeneira MD, Trzaskos JM, Newton RC, Decicco CP, Duan JJ. Chen XT, et al. Among authors: ribadeneira md. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1865-70. doi: 10.1016/j.bmcl.2007.01.041. Epub 2007 Jan 24. Bioorg Med Chem Lett. 2007. PMID: 17276676
Multicenter, phase 1 study of etavopivat (FT-4202) treatment for up to 12 weeks in patients with sickle cell disease.
Saraf SL, Hagar RW, Idowu M, Osunkwo I, Cruz K, Kuypers FA, Brown RC, Geib J, Ribadeneira MD, Schroeder P, Wu E, Forsyth S, Kelly PF, Kalfa TA, Telen MJ. Saraf SL, et al. Among authors: ribadeneira md. Blood Adv. 2024 Apr 19:bloodadvances.2023012467. doi: 10.1182/bloodadvances.2023012467. Online ahead of print. Blood Adv. 2024. PMID: 38640200
18 results