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Page 1
Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2R1441G mice.
Autophagy. 2021 Oct;17(10):3196-3220. doi: 10.1080/15548627.2020.1850008. Epub 2020 Dec 10.
Autophagy. 2021.
PMID: 33300446
Free PMC article.
LRRK2 mutant knock-in mouse models: therapeutic relevance in Parkinson's disease.
Chang EES, Ho PW, Liu HF, Pang SY, Leung CT, Malki Y, Choi ZY, Ramsden DB, Ho SL.
Chang EES, et al. Among authors: choi zy.
Transl Neurodegener. 2022 Feb 14;11(1):10. doi: 10.1186/s40035-022-00285-2.
Transl Neurodegener. 2022.
PMID: 35152914
Free PMC article.
Review.
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LRRK2, GBA and their interaction in the regulation of autophagy: implications on therapeutics in Parkinson's disease.
Pang SY, Lo RCN, Ho PW, Liu HF, Chang EES, Leung CT, Malki Y, Choi ZY, Wong WY, Kung MH, Ramsden DB, Ho SL.
Pang SY, et al. Among authors: choi zy.
Transl Neurodegener. 2022 Jan 31;11(1):5. doi: 10.1186/s40035-022-00281-6.
Transl Neurodegener. 2022.
PMID: 35101134
Free PMC article.
Review.
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Long-term inhibition of mutant LRRK2 hyper-kinase activity reduced mouse brain α-synuclein oligomers without adverse effects.
Ho PW, Chang EE, Leung CT, Liu H, Malki Y, Pang SY, Choi ZY, Liang Y, Lai WS, Ruan Y, Leung KM, Yung S, Mak JC, Kung MH, Ramsden DB, Ho SL.
Ho PW, et al. Among authors: choi zy.
NPJ Parkinsons Dis. 2022 Sep 10;8(1):115. doi: 10.1038/s41531-022-00386-9.
NPJ Parkinsons Dis. 2022.
PMID: 36088364
Free PMC article.
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Transcriptional Regulation of the Synaptic Vesicle Protein Synaptogyrin-3 (SYNGR3) Gene: The Effects of NURR1 on Its Expression.
Li L, Ho PW, Liu H, Pang SY, Chang EE, Choi ZY, Malki Y, Kung MH, Ramsden DB, Ho SL.
Li L, et al. Among authors: choi zy.
Int J Mol Sci. 2022 Mar 26;23(7):3646. doi: 10.3390/ijms23073646.
Int J Mol Sci. 2022.
PMID: 35409005
Free PMC article.
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In vivo overexpression of synaptogyrin-3 promotes striatal synaptic dopamine uptake in LRRK2R1441G mutant mouse model of Parkinson's disease.
Ho PW, Li L, Liu HF, Choi ZY, Chang EES, Pang SY, Malki Y, Leung CT, Kung MH, Ramsden DB, Ho SL.
Ho PW, et al. Among authors: choi zy.
Brain Behav. 2023 Feb;13(2):e2886. doi: 10.1002/brb3.2886. Epub 2023 Jan 9.
Brain Behav. 2023.
PMID: 36624932
Free PMC article.
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