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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2009 3
2010 1
2012 2
2013 1
2015 1
2017 1
2018 2
2019 1
2020 1
2021 1
2022 3
2023 1
2024 1

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20 results

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Page 1
Targeting the tubulin C-terminal tail by charged small molecules.
Li S, Mori M, Yang M, Elfazazi S, Hortigüela R, Chan P, Feng X, Risinger A, Yang Z, Oliva MÁ, Fernando Díaz J, Fang WS. Li S, et al. Among authors: hortiguela r. Org Biomol Chem. 2022 Dec 21;21(1):153-162. doi: 10.1039/d2ob01910h. Org Biomol Chem. 2022. PMID: 36472095
Universal scaling laws rule explosive growth in human cancers.
Pérez-García VM, Calvo GF, Bosque JJ, León-Triana O, Jiménez J, Perez-Beteta J, Belmonte-Beitia J, Valiente M, Zhu L, García-Gómez P, Sánchez-Gómez P, Hernández-San Miguel E, Hortigüela R, Azimzade Y, Molina-García D, Martinez Á, Rojas ÁA, de Mendivil AO, Vallette F, Schucht P, Murek M, Pérez-Cano M, Albillo D, Honguero Martínez AF, Jiménez Londoño GA, Arana E, García Vicente AM. Pérez-García VM, et al. Among authors: hortiguela r. Nat Phys. 2020 Dec;16(12):1232-1237. doi: 10.1038/s41567-020-0978-6. Epub 2020 Aug 10. Nat Phys. 2020. PMID: 33329756 Free PMC article.
IDP-410: a Novel Therapeutic Peptide that Alters N-MYC Stability and Reduces Angiogenesis and Tumor Progression in Glioblastomas.
Gargini R, Segura-Collar B, Garranzo-Asensio M, Hortigüela R, Iglesias-Hernández P, Lobato-Alonso D, Moreno-Raja M, Esteban-Martin S, Sepúlveda-Sánchez JM, Nevola L, Sánchez-Gómez P. Gargini R, et al. Among authors: hortiguela r. Neurotherapeutics. 2022 Jan;19(1):408-420. doi: 10.1007/s13311-021-01176-6. Epub 2022 Jan 31. Neurotherapeutics. 2022. PMID: 35099769 Free PMC article.
PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin.
Lucena-Agell D, Guillén MJ, Matesanz R, Álvarez-Bernad B, Hortigüela R, Avilés P, Martínez-Díez M, Santamaría-Núñez G, Contreras J, Plaza-Menacho I, Giménez-Abián JF, Oliva MA, Cuevas C, Díaz JF. Lucena-Agell D, et al. Among authors: hortiguela r. J Med Chem. 2024 Feb 22;67(4):2619-2630. doi: 10.1021/acs.jmedchem.3c01775. Epub 2024 Jan 31. J Med Chem. 2024. PMID: 38294341 Free PMC article.
The transcription factor LEF1 interacts with NFIX and switches isoforms during adult hippocampal neural stem cell quiescence.
García-Corzo L, Calatayud-Baselga I, Casares-Crespo L, Mora-Martínez C, Julián Escribano-Saiz J, Hortigüela R, Asenjo-Martínez A, Jordán-Pla A, Ercoli S, Flames N, López-Alonso V, Vilar M, Mira H. García-Corzo L, et al. Among authors: hortiguela r. Front Cell Dev Biol. 2022 Jul 22;10:912319. doi: 10.3389/fcell.2022.912319. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35938168 Free PMC article.
Ocoxin Modulates Cancer Stem Cells and M2 Macrophage Polarization in Glioblastoma.
Hernández-SanMiguel E, Gargini R, Cejalvo T, Segura-Collar B, Núñez-Hervada P, Hortigüela R, Sepúlveda-Sánchez JM, Hernández-Laín A, Pérez-Núñez A, Sanz E, Sánchez-Gómez P. Hernández-SanMiguel E, et al. Among authors: hortiguela r. Oxid Med Cell Longev. 2019 Aug 5;2019:9719730. doi: 10.1155/2019/9719730. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31467641 Free PMC article.
Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice.
Díaz-Moreno M, Hortigüela R, Gonçalves A, García-Carpio I, Manich G, García-Bermúdez E, Moreno-Estellés M, Eguiluz C, Vilaplana J, Pelegrí C, Vilar M, Mira H. Díaz-Moreno M, et al. Among authors: hortiguela r. Neurobiol Aging. 2013 Nov;34(11):2623-38. doi: 10.1016/j.neurobiolaging.2013.05.011. Epub 2013 Jun 22. Neurobiol Aging. 2013. PMID: 23796660
Modulation of taxane binding to tubulin curved and straight conformations by systematic 3'N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency.
Ma Y, Josa-Prado F, Essif JN, Liu S, Li S, Lucena-Agell D, Chan PY, Goossens K, Hortigüela R, Matesanz R, Wang Y, Gago F, Wang H, Risinger A, Diaz JF, Fang WS. Ma Y, et al. Among authors: hortiguela r. Eur J Med Chem. 2023 Nov 5;259:115668. doi: 10.1016/j.ejmech.2023.115668. Epub 2023 Jul 19. Eur J Med Chem. 2023. PMID: 37490800
20 results