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Page 1
Sialofucosylation Enables Platelet Binding to Myeloma Cells via P-Selectin and Suppresses NK Cell-Mediated Cytotoxicity.
Cancers (Basel). 2023 Apr 5;15(7):2154. doi: 10.3390/cancers15072154.
Cancers (Basel). 2023.
PMID: 37046814
Free PMC article.
Histone deacetylase complexes promote trinucleotide repeat expansions.
Debacker K, Frizzell A, Gleeson O, Kirkham-McCarthy L, Mertz T, Lahue RS.
Debacker K, et al. Among authors: kirkham mccarthy l.
PLoS Biol. 2012 Feb;10(2):e1001257. doi: 10.1371/journal.pbio.1001257. Epub 2012 Feb 21.
PLoS Biol. 2012.
PMID: 22363205
Free PMC article.
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CD38 knockout natural killer cells expressing an affinity optimized CD38 chimeric antigen receptor successfully target acute myeloid leukemia with reduced effector cell fratricide.
Gurney M, Stikvoort A, Nolan E, Kirkham-McCarthy L, Khoruzhenko S, Shivakumar R, Zweegman S, Van de Donk NWCJ, Mutis T, Szegezdi E, Sarkar S, O'Dwyer M.
Gurney M, et al. Among authors: kirkham mccarthy l.
Haematologica. 2022 Feb 1;107(2):437-445. doi: 10.3324/haematol.2020.271908.
Haematologica. 2022.
PMID: 33375774
Free PMC article.
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Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model.
Natoni A, Farrell ML, Harris S, Falank C, Kirkham-McCarthy L, Macauley MS, Reagan MR, O'Dwyer M.
Natoni A, et al. Among authors: kirkham mccarthy l.
Haematologica. 2020 Jan 31;105(2):457-467. doi: 10.3324/haematol.2018.212266. Print 2020.
Haematologica. 2020.
PMID: 31101754
Free PMC article.
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A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease mice.
Suelves N, Kirkham-McCarthy L, Lahue RS, Ginés S.
Suelves N, et al. Among authors: kirkham mccarthy l.
Sci Rep. 2017 Jul 20;7(1):6082. doi: 10.1038/s41598-017-05125-2.
Sci Rep. 2017.
PMID: 28729730
Free PMC article.
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The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide repeat expansions independently of homologous recombination.
Ye Y, Kirkham-McCarthy L, Lahue RS.
Ye Y, et al. Among authors: kirkham mccarthy l.
DNA Repair (Amst). 2016 Jul;43:1-8. doi: 10.1016/j.dnarep.2016.04.012. Epub 2016 May 2.
DNA Repair (Amst). 2016.
PMID: 27173583
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PSGL-1 decorated with sialyl Lewisa/x promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement.
O'Dwyer M, Kirkham-McCarthy L, Cerreto M, Foà R, Natoni A.
O'Dwyer M, et al. Among authors: kirkham mccarthy l.
Sci Rep. 2024 Jan 19;14(1):1756. doi: 10.1038/s41598-024-52212-2.
Sci Rep. 2024.
PMID: 38243063
Free PMC article.
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