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In situ genome sequencing resolves DNA sequence and structure in intact biological samples.
Payne AC, Chiang ZD, Reginato PL, Mangiameli SM, Murray EM, Yao CC, Markoulaki S, Earl AS, Labade AS, Jaenisch R, Church GM, Boyden ES, Buenrostro JD, Chen F. Payne AC, et al. Among authors: reginato pl. Science. 2021 Feb 26;371(6532):eaay3446. doi: 10.1126/science.aay3446. Epub 2020 Dec 31. Science. 2021. PMID: 33384301 Free PMC article.
3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing.
Nguyen HQ, Chattoraj S, Castillo D, Nguyen SC, Nir G, Lioutas A, Hershberg EA, Martins NMC, Reginato PL, Hannan M, Beliveau BJ, Church GM, Daugharthy ER, Marti-Renom MA, Wu CT. Nguyen HQ, et al. Among authors: reginato pl. Nat Methods. 2020 Aug;17(8):822-832. doi: 10.1038/s41592-020-0890-0. Epub 2020 Jul 27. Nat Methods. 2020. PMID: 32719531 Free PMC article.