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Stimulation of cholesterol biosynthesis in mitochondrial complex I-deficiency lowers reductive stress and improves motor function and survival in mice.
Biochim Biophys Acta Mol Basis Dis. 2021 Apr 1;1867(4):166062. doi: 10.1016/j.bbadis.2020.166062. Epub 2021 Jan 13.
Biochim Biophys Acta Mol Basis Dis. 2021.
PMID: 33385517
Free article.
Restoring cellular NAD(P)H levels by PPARα and LXRα stimulation to improve mitochondrial complex I deficiency.
Frambach SJCM, de Haas R, Smeitink JAM, Russel FGM, Schirris TJJ.
Frambach SJCM, et al.
Life Sci. 2022 Jul 1;300:120571. doi: 10.1016/j.lfs.2022.120571. Epub 2022 Apr 22.
Life Sci. 2022.
PMID: 35469913
Free article.
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Brothers in Arms: ABCA1- and ABCG1-Mediated Cholesterol Efflux as Promising Targets in Cardiovascular Disease Treatment.
Frambach SJCM, de Haas R, Smeitink JAM, Rongen GA, Russel FGM, Schirris TJJ.
Frambach SJCM, et al.
Pharmacol Rev. 2020 Jan;72(1):152-190. doi: 10.1124/pr.119.017897.
Pharmacol Rev. 2020.
PMID: 31831519
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Aberrant intestinal microbiota due to IL-1 receptor antagonist deficiency promotes IL-17- and TLR4-dependent arthritis.
Rogier R, Ederveen THA, Boekhorst J, Wopereis H, Scher JU, Manasson J, Frambach SJCM, Knol J, Garssen J, van der Kraan PM, Koenders MI, van den Berg WB, van Hijum SAFT, Abdollahi-Roodsaz S.
Rogier R, et al. Among authors: frambach sjcm.
Microbiome. 2017 Jun 23;5(1):63. doi: 10.1186/s40168-017-0278-2.
Microbiome. 2017.
PMID: 28645307
Free PMC article.
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Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice.
Frambach SJCM, van de Wal MAE, van den Broek PHH, Smeitink JAM, Russel FGM, de Haas R, Schirris TJJ.
Frambach SJCM, et al.
Biochim Biophys Acta Mol Basis Dis. 2020 Jun 1;1866(6):165727. doi: 10.1016/j.bbadis.2020.165727. Epub 2020 Feb 15.
Biochim Biophys Acta Mol Basis Dis. 2020.
PMID: 32070771
Free article.
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