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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
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2010 1
2011 3
2012 2
2013 1
2018 3
2019 2
2020 2
2021 4
2022 3
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2024 1

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24 results

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Page 1
Coactivator condensation at super-enhancers links phase separation and gene control.
Sabari BR, Dall'Agnese A, Boija A, Klein IA, Coffey EL, Shrinivas K, Abraham BJ, Hannett NM, Zamudio AV, Manteiga JC, Li CH, Guo YE, Day DS, Schuijers J, Vasile E, Malik S, Hnisz D, Lee TI, Cisse II, Roeder RG, Sharp PA, Chakraborty AK, Young RA. Sabari BR, et al. Among authors: klein ia. Science. 2018 Jul 27;361(6400):eaar3958. doi: 10.1126/science.aar3958. Epub 2018 Jun 21. Science. 2018. PMID: 29930091 Free PMC article.
Biomolecular Condensates and Cancer.
Boija A, Klein IA, Young RA. Boija A, et al. Among authors: klein ia. Cancer Cell. 2021 Feb 8;39(2):174-192. doi: 10.1016/j.ccell.2020.12.003. Epub 2021 Jan 7. Cancer Cell. 2021. PMID: 33417833 Free PMC article. Review.
Partitioning of cancer therapeutics in nuclear condensates.
Klein IA, Boija A, Afeyan LK, Hawken SW, Fan M, Dall'Agnese A, Oksuz O, Henninger JE, Shrinivas K, Sabari BR, Sagi I, Clark VE, Platt JM, Kar M, McCall PM, Zamudio AV, Manteiga JC, Coffey EL, Li CH, Hannett NM, Guo YE, Decker TM, Lee TI, Zhang T, Weng JK, Taatjes DJ, Chakraborty A, Sharp PA, Chang YT, Hyman AA, Gray NS, Young RA. Klein IA, et al. Science. 2020 Jun 19;368(6497):1386-1392. doi: 10.1126/science.aaz4427. Science. 2020. PMID: 32554597 Free PMC article.
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains.
Boija A, Klein IA, Sabari BR, Dall'Agnese A, Coffey EL, Zamudio AV, Li CH, Shrinivas K, Manteiga JC, Hannett NM, Abraham BJ, Afeyan LK, Guo YE, Rimel JK, Fant CB, Schuijers J, Lee TI, Taatjes DJ, Young RA. Boija A, et al. Among authors: klein ia. Cell. 2018 Dec 13;175(7):1842-1855.e16. doi: 10.1016/j.cell.2018.10.042. Epub 2018 Nov 15. Cell. 2018. PMID: 30449618 Free PMC article.
Biomolecular Condensates as Novel Antiviral Targets.
Martin EW, Iserman C, Olety B, Mitrea DM, Klein IA. Martin EW, et al. Among authors: klein ia. J Mol Biol. 2024 Feb 15;436(4):168380. doi: 10.1016/j.jmb.2023.168380. Epub 2023 Dec 5. J Mol Biol. 2024. PMID: 38061626 Review.
The transcription factor PAX8 promotes angiogenesis in ovarian cancer through interaction with SOX17.
Chaves-Moreira D, Mitchell MA, Arruza C, Rawat P, Sidoli S, Nameki R, Reddy J, Corona RI, Afeyan LK, Klein IA, Ma S, Winterhoff B, Konecny GE, Garcia BA, Brady DC, Lawrenson K, Morin PJ, Drapkin R. Chaves-Moreira D, et al. Among authors: klein ia. Sci Signal. 2022 Apr 5;15(728):eabm2496. doi: 10.1126/scisignal.abm2496. Epub 2022 Apr 5. Sci Signal. 2022. PMID: 35380877 Free PMC article.
Principles and functions of condensate modifying drugs.
Patel A, Mitrea D, Namasivayam V, Murcko MA, Wagner M, Klein IA. Patel A, et al. Among authors: klein ia. Front Mol Biosci. 2022 Nov 22;9:1007744. doi: 10.3389/fmolb.2022.1007744. eCollection 2022. Front Mol Biosci. 2022. PMID: 36483537 Free PMC article. Review.
CD-CODE: crowdsourcing condensate database and encyclopedia.
Rostam N, Ghosh S, Chow CFW, Hadarovich A, Landerer C, Ghosh R, Moon H, Hersemann L, Mitrea DM, Klein IA, Hyman AA, Toth-Petroczy A. Rostam N, et al. Among authors: klein ia. Nat Methods. 2023 May;20(5):673-676. doi: 10.1038/s41592-023-01831-0. Epub 2023 Apr 6. Nat Methods. 2023. PMID: 37024650 Free PMC article.
Modulating biomolecular condensates: a novel approach to drug discovery.
Mitrea DM, Mittasch M, Gomes BF, Klein IA, Murcko MA. Mitrea DM, et al. Among authors: klein ia. Nat Rev Drug Discov. 2022 Nov;21(11):841-862. doi: 10.1038/s41573-022-00505-4. Epub 2022 Aug 16. Nat Rev Drug Discov. 2022. PMID: 35974095 Free PMC article. Review.
Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes.
Zamudio AV, Dall'Agnese A, Henninger JE, Manteiga JC, Afeyan LK, Hannett NM, Coffey EL, Li CH, Oksuz O, Sabari BR, Boija A, Klein IA, Hawken SW, Spille JH, Decker TM, Cisse II, Abraham BJ, Lee TI, Taatjes DJ, Schuijers J, Young RA. Zamudio AV, et al. Among authors: klein ia. Mol Cell. 2019 Dec 5;76(5):753-766.e6. doi: 10.1016/j.molcel.2019.08.016. Epub 2019 Sep 25. Mol Cell. 2019. PMID: 31563432 Free PMC article.
24 results