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Suppression of superoxide/hydrogen peroxide production at mitochondrial site IQ decreases fat accumulation, improves glucose tolerance and normalizes fasting insulin concentration in mice fed a high-fat diet.
Watson MA, Brar H, Gibbs ET 2nd, Wong HS, Dighe PA, McKibben B, Riedmaier S, Siu A, Polakowski JS, Segreti JA, Liu X, Chung S, Pliushchev YM, Gesmundo N, Wang Z, Vortherms TA, Brand MD. Watson MA, et al. Among authors: mckibben b. Free Radic Biol Med. 2023 Aug 1;204:276-286. doi: 10.1016/j.freeradbiomed.2023.05.022. Epub 2023 May 20. Free Radic Biol Med. 2023. PMID: 37217089 Free article.
Superoxide produced by mitochondrial site IQ inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice.
Wong HS, Mezera V, Dighe P, Melov S, Gerencser AA, Sweis RF, Pliushchev M, Wang Z, Esbenshade T, McKibben B, Riedmaier S, Brand MD. Wong HS, et al. Among authors: mckibben b. Free Radic Biol Med. 2021 Feb 20;164:223-232. doi: 10.1016/j.freeradbiomed.2020.12.447. Epub 2021 Jan 6. Free Radic Biol Med. 2021. PMID: 33421588 Free article.
CXCR7 agonists inhibit the function of CXCL12 by down-regulation of CXCR4.
Uto-Konomi A, McKibben B, Wirtz J, Sato Y, Takano A, Nanki T, Suzuki S. Uto-Konomi A, et al. Among authors: mckibben b. Biochem Biophys Res Commun. 2013 Feb 22;431(4):772-6. doi: 10.1016/j.bbrc.2013.01.032. Epub 2013 Jan 16. Biochem Biophys Res Commun. 2013. PMID: 23333329
Diastereoselective Synthesis of α-Quaternary Aziridine-2-carboxylates via Aza-Corey-Chaykovsky Aziridination of N-tert-Butanesulfinyl Ketimino Esters.
Marsini MA, Reeves JT, Desrosiers JN, Herbage MA, Savoie J, Li Z, Fandrick KR, Sader CA, McKibben B, Gao DA, Cui J, Gonnella NC, Lee H, Wei X, Roschangar F, Lu BZ, Senanayake CH. Marsini MA, et al. Among authors: mckibben b. Org Lett. 2015 Nov 20;17(22):5614-7. doi: 10.1021/acs.orglett.5b02838. Epub 2015 Nov 11. Org Lett. 2015. PMID: 26558319