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Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma.
Agliardi G, Liuzzi AR, Hotblack A, De Feo D, Núñez N, Stowe CL, Friebel E, Nannini F, Rindlisbacher L, Roberts TA, Ramasawmy R, Williams IP, Siow BM, Lythgoe MF, Kalber TL, Quezada SA, Pule MA, Tugues S, Straathof K, Becher B. Agliardi G, et al. Among authors: williams ip. Nat Commun. 2021 Jan 19;12(1):444. doi: 10.1038/s41467-020-20599-x. Nat Commun. 2021. PMID: 33469002 Free PMC article.
Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma.
Khair DO, Bax HJ, Mele S, Crescioli S, Pellizzari G, Khiabany A, Nakamura M, Harris RJ, French E, Hoffmann RM, Williams IP, Cheung A, Thair B, Beales CT, Touizer E, Signell AW, Tasnova NL, Spicer JF, Josephs DH, Geh JL, MacKenzie Ross A, Healy C, Papa S, Lacy KE, Karagiannis SN. Khair DO, et al. Among authors: williams ip. Front Immunol. 2019 Mar 19;10:453. doi: 10.3389/fimmu.2019.00453. eCollection 2019. Front Immunol. 2019. PMID: 30941125 Free PMC article. Review.
Tunable control of CAR T cell activity through tetracycline mediated disruption of protein-protein interaction.
Hotblack A, Kokalaki EK, Palton MJ, Cheung GW, Williams IP, Manzoor S, Grothier TI, Piapi A, Fiaccadori V, Wawrzyniecka P, Roddy HA, Agliardi G, Roddie C, Onuoha S, Thomas S, Cordoba S, Pule M. Hotblack A, et al. Among authors: williams ip. Sci Rep. 2021 Nov 9;11(1):21902. doi: 10.1038/s41598-021-01418-9. Sci Rep. 2021. PMID: 34754016 Free PMC article.
Subsurface radar sounding of the south polar layered deposits of Mars.
Plaut JJ, Picardi G, Safaeinili A, Ivanov AB, Milkovich SM, Cicchetti A, Kofman W, Mouginot J, Farrell WM, Phillips RJ, Clifford SM, Frigeri A, Orosei R, Federico C, Williams IP, Gurnett DA, Nielsen E, Hagfors T, Heggy E, Stofan ER, Plettemeier D, Watters TR, Leuschen CJ, Edenhofer P. Plaut JJ, et al. Among authors: williams ip. Science. 2007 Apr 6;316(5821):92-5. doi: 10.1126/science.1139672. Epub 2007 Mar 15. Science. 2007. PMID: 17363628