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Year Number of Results
2013 1
2014 1
2017 1
2019 5
2020 4
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2022 4
2023 1
2024 0

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16 results

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Page 1
Defining 'T cell exhaustion'.
Blank CU, Haining WN, Held W, Hogan PG, Kallies A, Lugli E, Lynn RC, Philip M, Rao A, Restifo NP, Schietinger A, Schumacher TN, Schwartzberg PL, Sharpe AH, Speiser DE, Wherry EJ, Youngblood BA, Zehn D. Blank CU, et al. Among authors: youngblood ba. Nat Rev Immunol. 2019 Nov;19(11):665-674. doi: 10.1038/s41577-019-0221-9. Epub 2019 Sep 30. Nat Rev Immunol. 2019. PMID: 31570879 Free PMC article. Review.
Functional T cells are capable of supernumerary cell division and longevity.
Soerens AG, Künzli M, Quarnstrom CF, Scott MC, Swanson L, Locquiao JJ, Ghoneim HE, Zehn D, Youngblood B, Vezys V, Masopust D. Soerens AG, et al. Among authors: youngblood b. Nature. 2023 Feb;614(7949):762-766. doi: 10.1038/s41586-022-05626-9. Epub 2023 Jan 18. Nature. 2023. PMID: 36653453
Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans.
Galletti G, De Simone G, Mazza EMC, Puccio S, Mezzanotte C, Bi TM, Davydov AN, Metsger M, Scamardella E, Alvisi G, De Paoli F, Zanon V, Scarpa A, Camisa B, Colombo FS, Anselmo A, Peano C, Polletti S, Mavilio D, Gattinoni L, Boi SK, Youngblood BA, Jones RE, Baird DM, Gostick E, Llewellyn-Lacey S, Ladell K, Price DA, Chudakov DM, Newell EW, Casucci M, Lugli E. Galletti G, et al. Among authors: youngblood ba. Nat Immunol. 2020 Dec;21(12):1552-1562. doi: 10.1038/s41590-020-0791-5. Epub 2020 Oct 12. Nat Immunol. 2020. PMID: 33046887 Free PMC article.
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.
Alfei F, Kanev K, Hofmann M, Wu M, Ghoneim HE, Roelli P, Utzschneider DT, von Hoesslin M, Cullen JG, Fan Y, Eisenberg V, Wohlleber D, Steiger K, Merkler D, Delorenzi M, Knolle PA, Cohen CJ, Thimme R, Youngblood B, Zehn D. Alfei F, et al. Among authors: youngblood b. Nature. 2019 Jul;571(7764):265-269. doi: 10.1038/s41586-019-1326-9. Epub 2019 Jun 17. Nature. 2019. PMID: 31207605
Defining the Molecular Hallmarks of T-Cell Memory.
Zebley CC, Akondy RS, Youngblood BA, Kissick HT. Zebley CC, et al. Among authors: youngblood ba. Cold Spring Harb Perspect Biol. 2022 Mar 1;14(3):a037804. doi: 10.1101/cshperspect.a037804. Cold Spring Harb Perspect Biol. 2022. PMID: 34127444 Free PMC article. Review.
MEK inhibition reprograms CD8+ T lymphocytes into memory stem cells with potent antitumor effects.
Verma V, Jafarzadeh N, Boi S, Kundu S, Jiang Z, Fan Y, Lopez J, Nandre R, Zeng P, Alolaqi F, Ahmad S, Gaur P, Barry ST, Valge-Archer VE, Smith PD, Banchereau J, Mkrtichyan M, Youngblood B, Rodriguez PC, Gupta S, Khleif SN. Verma V, et al. Among authors: youngblood b. Nat Immunol. 2021 Jan;22(1):53-66. doi: 10.1038/s41590-020-00818-9. Epub 2020 Nov 23. Nat Immunol. 2021. PMID: 33230330 Free PMC article.
Stem, Effector, and Hybrid States of Memory CD8+ T Cells.
Lugli E, Galletti G, Boi SK, Youngblood BA. Lugli E, et al. Among authors: youngblood ba. Trends Immunol. 2020 Jan;41(1):17-28. doi: 10.1016/j.it.2019.11.004. Epub 2019 Dec 4. Trends Immunol. 2020. PMID: 31810790 Free PMC article. Review.
Phase I Clinical Trial of DNA Methyltransferase Inhibitor Decitabine and PARP Inhibitor Talazoparib Combination Therapy in Relapsed/Refractory Acute Myeloid Leukemia.
Baer MR, Kogan AA, Bentzen SM, Mi T, Lapidus RG, Duong VH, Emadi A, Niyongere S, O'Connell CL, Youngblood BA, Baylin SB, Rassool FV. Baer MR, et al. Among authors: youngblood ba. Clin Cancer Res. 2022 Apr 1;28(7):1313-1322. doi: 10.1158/1078-0432.CCR-21-3729. Clin Cancer Res. 2022. PMID: 35091444 Free PMC article. Clinical Trial.
Developmental plasticity allows outside-in immune responses by resident memory T cells.
Fonseca R, Beura LK, Quarnstrom CF, Ghoneim HE, Fan Y, Zebley CC, Scott MC, Fares-Frederickson NJ, Wijeyesinghe S, Thompson EA, Borges da Silva H, Vezys V, Youngblood B, Masopust D. Fonseca R, et al. Among authors: youngblood b. Nat Immunol. 2020 Apr;21(4):412-421. doi: 10.1038/s41590-020-0607-7. Epub 2020 Feb 17. Nat Immunol. 2020. PMID: 32066954 Free PMC article.
Antigen Density Dictates Immune Responsiveness following Red Blood Cell Transfusion.
Arthur CM, Patel SR, Smith NH, Bennett A, Kamili NA, Mener A, Gerner-Smidt C, Sullivan HC, Hale JS, Wieland A, Youngblood B, Zimring JC, Hendrickson JE, Stowell SR. Arthur CM, et al. Among authors: youngblood b. J Immunol. 2017 Apr 1;198(7):2671-2680. doi: 10.4049/jimmunol.1601736. Epub 2017 Mar 1. J Immunol. 2017. PMID: 28250159 Free PMC article.
16 results