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ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation.
van Vliet AR, Chiduza GN, Maslen SL, Pye VE, Joshi D, De Tito S, Jefferies HBJ, Christodoulou E, Roustan C, Punch E, Hervás JH, O'Reilly N, Skehel JM, Cherepanov P, Tooze SA. van Vliet AR, et al. Among authors: jefferies hbj. Mol Cell. 2022 Nov 17;82(22):4324-4339.e8. doi: 10.1016/j.molcel.2022.10.017. Epub 2022 Nov 7. Mol Cell. 2022. PMID: 36347259 Free article.
Assessing mammalian autophagy.
Tooze SA, Dooley HC, Jefferies HB, Joachim J, Judith D, Lamb CA, Razi M, Wirth M. Tooze SA, et al. Among authors: jefferies hb. Methods Mol Biol. 2015;1270:155-65. doi: 10.1007/978-1-4939-2309-0_12. Methods Mol Biol. 2015. PMID: 25702116
Exploring the ATG9A interactome uncovers interaction with VPS13A.
van Vliet AR, Jefferies HBJ, Faull PA, Chadwick J, Ibrahim F, Skehel MJ, Tooze SA. van Vliet AR, et al. Among authors: jefferies hbj. J Cell Sci. 2024 Feb 15;137(4):jcs261081. doi: 10.1242/jcs.261081. Epub 2024 Feb 22. J Cell Sci. 2024. PMID: 38294121 Free PMC article.
Trafficking and signaling in mammalian autophagy.
Tooze SA, Jefferies HB, Kalie E, Longatti A, McAlpine FE, McKnight NC, Orsi A, Polson HE, Razi M, Robinson DJ, Webber JL. Tooze SA, et al. Among authors: jefferies hb. IUBMB Life. 2010 Jul;62(7):503-8. doi: 10.1002/iub.334. IUBMB Life. 2010. PMID: 20552641 Free article. Review.
A switch from canonical to noncanonical autophagy shapes B cell responses.
Martinez-Martin N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, Tsui C, Burbage M, Keppler SJ, Montaner B, Jefferies HB, Nair U, Zhao YG, Domart MC, Collinson L, Bruckbauer A, Tooze SA, Batista FD. Martinez-Martin N, et al. Among authors: jefferies hb. Science. 2017 Feb 10;355(6325):641-647. doi: 10.1126/science.aal3908. Science. 2017. PMID: 28183981 Free PMC article.
MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma.
New M, Van Acker T, Sakamaki JI, Jiang M, Saunders RE, Long J, Wang VM, Behrens A, Cerveira J, Sudhakar P, Korcsmaros T, Jefferies HBJ, Ryan KM, Howell M, Tooze SA. New M, et al. Among authors: jefferies hbj. Cancer Res. 2019 Apr 15;79(8):1884-1898. doi: 10.1158/0008-5472.CAN-18-2553. Epub 2019 Feb 14. Cancer Res. 2019. PMID: 30765601 Free PMC article.
Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
Wirth M, Mouilleron S, Zhang W, Sjøttem E, Princely Abudu Y, Jain A, Lauritz Olsvik H, Bruun JA, Razi M, Jefferies HBJ, Lee R, Joshi D, O'Reilly N, Johansen T, Tooze SA. Wirth M, et al. Among authors: jefferies hbj. J Mol Biol. 2021 Jun 25;433(13):166987. doi: 10.1016/j.jmb.2021.166987. Epub 2021 Apr 24. J Mol Biol. 2021. PMID: 33845085 Free PMC article.
Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy.
Joachim J, Razi M, Judith D, Wirth M, Calamita E, Encheva V, Dynlacht BD, Snijders AP, O'Reilly N, Jefferies HBJ, Tooze SA. Joachim J, et al. Among authors: jefferies hbj. Curr Biol. 2017 Jul 24;27(14):2123-2136.e7. doi: 10.1016/j.cub.2017.06.021. Epub 2017 Jul 14. Curr Biol. 2017. PMID: 28712572 Free PMC article.
17 results