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Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin.
Garcia-Diaz C, Pöysti A, Mereu E, Clements MP, Brooks LJ, Galvez-Cancino F, Castillo SP, Tang W, Beattie G, Courtot L, Ruiz S, Roncaroli F, Yuan Y, Marguerat S, Quezada SA, Heyn H, Parrinello S. Garcia-Diaz C, et al. Among authors: clements mp. Cell Rep. 2023 May 30;42(5):112472. doi: 10.1016/j.celrep.2023.112472. Epub 2023 May 5. Cell Rep. 2023. PMID: 37149862 Free article.
Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells.
Amodeo V, Davies T, Martinez-Segura A, Clements MP, Ragdale HS, Bailey A, Dos Santos MS, MacRae JI, Mokochinski J, Kramer H, Garcia-Diaz C, Gould AP, Marguerat S, Parrinello S. Amodeo V, et al. Among authors: clements mp. Dev Cell. 2023 May 22;58(10):836-846.e6. doi: 10.1016/j.devcel.2023.03.021. Epub 2023 Apr 20. Dev Cell. 2023. PMID: 37084728 Free PMC article.
The white matter is a pro-differentiative niche for glioblastoma.
Brooks LJ, Clements MP, Burden JJ, Kocher D, Richards L, Devesa SC, Zakka L, Woodberry M, Ellis M, Jaunmuktane Z, Brandner S, Morrison G, Pollard SM, Dirks PB, Marguerat S, Parrinello S. Brooks LJ, et al. Among authors: clements mp. Nat Commun. 2021 Apr 12;12(1):2184. doi: 10.1038/s41467-021-22225-w. Nat Commun. 2021. PMID: 33846316 Free PMC article.
LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells.
Marqués-Torrejón MÁ, Williams CAC, Southgate B, Alfazema N, Clements MP, Garcia-Diaz C, Blin C, Arranz-Emparan N, Fraser J, Gammoh N, Parrinello S, Pollard SM. Marqués-Torrejón MÁ, et al. Among authors: clements mp. Nat Commun. 2021 May 10;12(1):2594. doi: 10.1038/s41467-021-22813-w. Nat Commun. 2021. PMID: 33972529 Free PMC article.
Author Correction: The white matter is a pro-differentiative niche for glioblastoma.
Brooks LJ, Clements MP, Burden JJ, Kocher D, Richards L, Devesa SC, Zakka L, Woodberry M, Ellis M, Jaunmuktane Z, Brandner S, Morrison G, Pollard SM, Dirks PB, Marguerat S, Parrinello S. Brooks LJ, et al. Among authors: clements mp. Nat Commun. 2022 Apr 14;13(1):2163. doi: 10.1038/s41467-022-29916-y. Nat Commun. 2022. PMID: 35422055 Free PMC article. No abstract available.
EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells.
Krusche B, Ottone C, Clements MP, Johnstone ER, Goetsch K, Lieven H, Mota SG, Singh P, Khadayate S, Ashraf A, Davies T, Pollard SM, De Paola V, Roncaroli F, Martinez-Torrecuadrada J, Bertone P, Parrinello S. Krusche B, et al. Among authors: clements mp. Elife. 2016 Jun 28;5:e14845. doi: 10.7554/eLife.14845. Elife. 2016. PMID: 27350048 Free PMC article.