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Synthesis of portimines reveals the basis of their anti-cancer activity.
Tang J, Li W, Chiu TY, Martínez-Peña F, Luo Z, Chong CT, Wei Q, Gazaniga N, West TJ, See YY, Lairson LL, Parker CG, Baran PS. Tang J, et al. Among authors: chiu ty. Nature. 2023 Oct;622(7983):507-513. doi: 10.1038/s41586-023-06535-1. Epub 2023 Sep 20. Nature. 2023. PMID: 37730997
MLN4924, a Novel NEDD8-activating enzyme inhibitor, exhibits antitumor activity and enhances cisplatin-induced cytotoxicity in human cervical carcinoma: in vitro and in vivo study.
Lin WC, Kuo KL, Shi CS, Wu JT, Hsieh JT, Chang HC, Liao SM, Chou CT, Chiang CK, Chiu WS, Chiu TY, Pu YS, Ho IL, Wang ZH, Chang SC, Liu SH, Jeng YM, Huang KH. Lin WC, et al. Among authors: chiu ty. Am J Cancer Res. 2015 Oct 15;5(11):3350-62. eCollection 2015. Am J Cancer Res. 2015. PMID: 26807316 Free PMC article.