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Page 1
Somatic gene mutations expose cytoplasmic DNA to co-opt the cGAS/STING/NLRP3 axis in myelodysplastic syndromes.
JCI Insight. 2022 Aug 8;7(15):e159430. doi: 10.1172/jci.insight.159430.
JCI Insight. 2022.
PMID: 35788117
Free PMC article.
Oxidized Mitochondrial DNA Engages TLR9 to Activate the NLRP3 Inflammasome in Myelodysplastic Syndromes.
Ward GA, Dalton RP 3rd, Meyer BS, McLemore AF, Aldrich AL, Lam NB, Onimus AH, Vincelette ND, Trinh TL, Chen X, Calescibetta AR, Christiansen SM, Hou HA, Johnson JO, Wright KL, Padron E, Eksioglu EA, List AF.
Ward GA, et al.
Int J Mol Sci. 2023 Feb 15;24(4):3896. doi: 10.3390/ijms24043896.
Int J Mol Sci. 2023.
PMID: 36835307
Free PMC article.
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Oxidized mitochondrial DNA released after inflammasome activation is a disease biomarker for myelodysplastic syndromes.
Ward GA, McGraw KL, Abbas-Aghababazadeh F, Meyer BS, McLemore AF, Vincelette ND, Lam NB, Aldrich AL, Al Ali NH, Padron E, Pinilla-Ibarz J, Masala E, Santini V, Kosmider O, Fontenay M, Fenaux P, Johnson J, Fridley BL, List AF.
Ward GA, et al.
Blood Adv. 2021 Apr 27;5(8):2216-2228. doi: 10.1182/bloodadvances.2020003475.
Blood Adv. 2021.
PMID: 33890980
Free PMC article.
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Dual Targeting of WEE1 and PLK1 by AZD1775 Elicits Single Agent Cellular Anticancer Activity.
Wright G, Golubeva V, Remsing Rix LL, Berndt N, Luo Y, Ward GA, Gray JE, Schonbrunn E, Lawrence HR, Monteiro ANA, Rix U.
Wright G, et al. Among authors: ward ga.
ACS Chem Biol. 2017 Jul 21;12(7):1883-1892. doi: 10.1021/acschembio.7b00147. Epub 2017 Jun 7.
ACS Chem Biol. 2017.
PMID: 28557434
Free PMC article.
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Assessment of ASC specks as a putative biomarker of pyroptosis in myelodysplastic syndromes: an observational cohort study.
Basiorka AA, McGraw KL, Abbas-Aghababazadeh F, McLemore AF, Vincelette ND, Ward GA, Eksioglu EA, Sallman DA, Ali NA, Padron E, Pinilla-Ibarz J, Komrokji R, Masala E, Santini V, Kosmider O, Fontenay M, Fenaux P, Sokol L, Wei S, Fridley B, List AF.
Basiorka AA, et al. Among authors: ward ga.
Lancet Haematol. 2018 Sep;5(9):e393-e402. doi: 10.1016/S2352-3026(18)30109-1. Epub 2018 Jul 30.
Lancet Haematol. 2018.
PMID: 30072146
Free PMC article.
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Circulating Oxidized mtDNA is Associated Broadly with Cardiovascular Disease in a Longitudinal Cohort Study of Psoriasis.
Lateef SS, Ward GA, Li H, Pantoja C, Florida E, Hong CG, Rodante J, Keel A, Chen MY, Sorokin AV, Playford MP, Mehta NN.
Lateef SS, et al. Among authors: ward ga.
JID Innov. 2023 Nov 3;4(1):100243. doi: 10.1016/j.xjidi.2023.100243. eCollection 2024 Jan.
JID Innov. 2023.
PMID: 38162017
Free PMC article.
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