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eileen a ren[Author]
(3 results)?
Cerebral Cavernous Malformation: From Mechanism to Therapy.
Circ Res. 2021 Jun 25;129(1):195-215. doi: 10.1161/CIRCRESAHA.121.318174. Epub 2021 Jun 24.
Circ Res. 2021.
PMID: 34166073
Free PMC article.
Review.
PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Ren AA, Snellings DA, Su YS, Hong CC, Castro M, Tang AT, Detter MR, Hobson N, Girard R, Romanos S, Lightle R, Moore T, Shenkar R, Benavides C, Beaman MM, Müller-Fielitz H, Chen M, Mericko P, Yang J, Sung DC, Lawton MT, Ruppert JM, Schwaninger M, Körbelin J, Potente M, Awad IA, Marchuk DA, Kahn ML.
Ren AA, et al.
Nature. 2021 Jun;594(7862):271-276. doi: 10.1038/s41586-021-03562-8. Epub 2021 Apr 28.
Nature. 2021.
PMID: 33910229
Free PMC article.
Item in Clipboard
mTORC1 Inhibitor Rapamycin Inhibits Growth of Cerebral Cavernous Malformation in Adult Mice.
Li L, Ren AA, Gao S, Su YS, Yang J, Bockman J, Mericko-Ishizuka P, Griffin J, Shenkar R, Alcazar R, Moore T, Lightle R, DeBiasse D, Awad IA, Marchuk DA, Kahn ML, Burkhardt JK.
Li L, et al. Among authors: ren aa.
Stroke. 2023 Nov;54(11):2906-2917. doi: 10.1161/STROKEAHA.123.044108. Epub 2023 Sep 25.
Stroke. 2023.
PMID: 37746705
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Sinusoidal and lymphatic vessel growth is controlled by reciprocal VEGF-C-CDH5 inhibition.
Sung DC, Chen M, Dominguez MH, Mahadevan A, Chen X, Yang J, Gao S, Ren AA, Tang AT, Mericko P, Patton R, Lee M, Jannaway M, Nottebaum A, Vestweber D, Scallan JP, Kahn ML.
Sung DC, et al. Among authors: ren aa.
Nat Cardiovasc Res. 2022 Nov;1(11):1006-1021. doi: 10.1038/s44161-022-00147-0. Epub 2022 Nov 11.
Nat Cardiovasc Res. 2022.
PMID: 36910472
Free PMC article.
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Developmental venous anomalies are a genetic primer for cerebral cavernous malformations.
Snellings DA, Girard R, Lightle R, Srinath A, Romanos S, Li Y, Chen C, Ren AA, Kahn ML, Awad IA, Marchuk DA.
Snellings DA, et al. Among authors: ren aa.
Nat Cardiovasc Res. 2022 Mar;1:246-252. doi: 10.1038/s44161-022-00035-7. Epub 2022 Mar 14.
Nat Cardiovasc Res. 2022.
PMID: 35355835
Free PMC article.
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Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.
Hong CC, Tang AT, Detter MR, Choi JP, Wang R, Yang X, Guerrero AA, Wittig CF, Hobson N, Girard R, Lightle R, Moore T, Shenkar R, Polster SP, Goddard LM, Ren AA, Leu NA, Sterling S, Yang J, Li L, Chen M, Mericko-Ishizuka P, Dow LE, Watanabe H, Schwaninger M, Min W, Marchuk DA, Zheng X, Awad IA, Kahn ML.
Hong CC, et al. Among authors: ren aa.
J Exp Med. 2020 Oct 5;217(10):e20200140. doi: 10.1084/jem.20200140.
J Exp Med. 2020.
PMID: 32648916
Free PMC article.
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