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Target selection for FDA-approved medicines.
Kinch MS, Hoyer D, Patridge E, Plummer M. Kinch MS, et al. Among authors: hoyer d. Drug Discov Today. 2015 Jul;20(7):784-9. doi: 10.1016/j.drudis.2014.11.001. Epub 2014 Nov 11. Drug Discov Today. 2015. PMID: 25462532 Review.
An overview of FDA-approved new molecular entities: 1827-2013.
Kinch MS, Haynesworth A, Kinch SL, Hoyer D. Kinch MS, et al. Among authors: hoyer d. Drug Discov Today. 2014 Aug;19(8):1033-9. doi: 10.1016/j.drudis.2014.03.018. Epub 2014 Mar 26. Drug Discov Today. 2014. PMID: 24680947 Review.
Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function.
Schiapparelli P, Pirman NL, Mohler K, Miranda-Herrera PA, Zarco N, Kilic O, Miller C, Shah SR, Rogulina S, Hungerford W, Abriola L, Hoyer D, Turk BE, Guerrero-Cázares H, Isaacs FJ, Quiñones-Hinojosa A, Levchenko A, Rinehart J. Schiapparelli P, et al. Among authors: hoyer d. Cell Rep. 2021 Jul 20;36(3):109416. doi: 10.1016/j.celrep.2021.109416. Cell Rep. 2021. PMID: 34289367 Free PMC article.
A γ-Lactam Siderophore Antibiotic Effective against Multidrug-Resistant Gram-Negative Bacilli.
Goldberg JA, Nguyen H, Kumar V, Spencer EJ, Hoyer D, Marshall EK, Cmolik A, O'Shea M, Marshall SH, Hujer AM, Hujer KM, Rudin SD, Domitrovic TN, Bethel CR, Papp-Wallace KM, Logan LK, Perez F, Jacobs MR, van Duin D, Kreiswirth BM, Bonomo RA, Plummer MS, van den Akker F. Goldberg JA, et al. Among authors: hoyer d. J Med Chem. 2020 Jun 11;63(11):5990-6002. doi: 10.1021/acs.jmedchem.0c00255. Epub 2020 Jun 2. J Med Chem. 2020. PMID: 32420736 Free PMC article.
A history of drug development in four acts.
Kinch MS, Hoyer D. Kinch MS, et al. Among authors: hoyer d. Drug Discov Today. 2015 Oct;20(10):1163-8. doi: 10.1016/j.drudis.2015.04.003. Epub 2015 Apr 20. Drug Discov Today. 2015. PMID: 25908577 No abstract available.
A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp.
Goldberg JA, Kumar V, Spencer EJ, Hoyer D, Marshall SH, Hujer AM, Hujer KM, Bethel CR, Papp-Wallace KM, Perez F, Jacobs MR, van Duin D, Kreiswirth BN, van den Akker F, Plummer MS, Bonomo RA. Goldberg JA, et al. Among authors: hoyer d. Eur J Med Chem. 2021 Aug 5;220:113436. doi: 10.1016/j.ejmech.2021.113436. Epub 2021 Apr 8. Eur J Med Chem. 2021. PMID: 33933754
24 results