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Page 1
Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance.
Nat Commun. 2021 May 13;12(1):2782. doi: 10.1038/s41467-021-23044-9.
Nat Commun. 2021.
PMID: 33986293
Free PMC article.
The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects.
Van Der Byl W, Nüssing S, Peters TJ, Ahn A, Li H, Ledergor G, David E, Koh AS, Wagle MV, Deguit CDT, de Menezes MN, Travers A, Sampurno S, Ramsbottom KM, Li R, Kallies A, Beavis PA, Jungmann R, Bastings MMC, Belz GT, Goel S, Trapani JA, Crabtree GR, Chang HY, Amit I, Goodnow CC, Luciani F, Parish IA.
Van Der Byl W, et al. Among authors: wagle mv.
Immunity. 2024 May 16:S1074-7613(24)00231-0. doi: 10.1016/j.immuni.2024.04.026. Online ahead of print.
Immunity. 2024.
PMID: 38776918
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The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8+ T Cell Tolerance Checkpoint to High-Dose Antigen.
Wagle MV, Marchingo JM, Howitt J, Tan SS, Goodnow CC, Parish IA.
Wagle MV, et al.
Cell Rep. 2018 Jul 17;24(3):577-584. doi: 10.1016/j.celrep.2018.06.060.
Cell Rep. 2018.
PMID: 30021156
Free PMC article.
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FOXO3 is differentially required for CD8+ T-cell death during tolerance versus immunity.
Wagle MV, Parish IA.
Wagle MV, et al.
Immunol Cell Biol. 2016 Oct;94(9):895-899. doi: 10.1038/icb.2016.53. Epub 2016 Jun 21.
Immunol Cell Biol. 2016.
PMID: 27323690
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Effective Priming of Herpes Simplex Virus-Specific CD8+ T Cells In Vivo Does Not Require Infected Dendritic Cells.
Whitney PG, Makhlouf C, MacLeod B, Ma JZ, Gressier E, Greyer M, Hochheiser K, Bachem A, Zaid A, Voehringer D, Heath WR, Wagle MV, Parish I, Russell TA, Smith SA, Tscharke DC, Gebhardt T, Bedoui S.
Whitney PG, et al. Among authors: wagle mv.
J Virol. 2018 Jan 17;92(3):e01508-17. doi: 10.1128/JVI.01508-17. Print 2018 Feb 1.
J Virol. 2018.
PMID: 29142130
Free PMC article.
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Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion.
Miosge LA, Sontani Y, Chuah A, Horikawa K, Russell TA, Mei Y, Wagle MV, Howard DR, Enders A, Tscharke DC, Goodnow CC, Parish IA.
Miosge LA, et al. Among authors: wagle mv.
Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5216-E5225. doi: 10.1073/pnas.1705795114. Epub 2017 Jun 12.
Proc Natl Acad Sci U S A. 2017.
PMID: 28607084
Free PMC article.
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