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SMAD4 is critical in suppression of BRAF-V600E serrated tumorigenesis.
Tong K, Kothari OA, Haro KS, Panda A, Bandari MM, Carrick JN, Hur JJ, Zhang L, Chan CS, Xing J, Gatza ML, Ganesan S, Verzi MP. Tong K, et al. Among authors: hur jj. Oncogene. 2021 Oct;40(41):6034-6048. doi: 10.1038/s41388-021-01997-x. Epub 2021 Aug 27. Oncogene. 2021. PMID: 34453124 Free PMC article.
The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac.
Chen L, Luo S, Dupre A, Vasoya RP, Parthasarathy A, Aita R, Malhotra R, Hur J, Toke NH, Chiles E, Yang M, Cao W, Flores J, Ellison CE, Gao N, Sahota A, Su X, Bonder EM, Verzi MP. Chen L, et al. Among authors: hur j. Nat Commun. 2021 May 17;12(1):2886. doi: 10.1038/s41467-021-22761-5. Nat Commun. 2021. PMID: 34001900 Free PMC article.
Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes.
Zheng CL, Wang NJ, Chung J, Moslehi H, Sanborn JZ, Hur JS, Collisson EA, Vemula SS, Naujokas A, Chiotti KE, Cheng JB, Fassihi H, Blumberg AJ, Bailey CV, Fudem GM, Mihm FG, Cunningham BB, Neuhaus IM, Liao W, Oh DH, Cleaver JE, LeBoit PE, Costello JF, Lehmann AR, Gray JW, Spellman PT, Arron ST, Huh N, Purdom E, Cho RJ. Zheng CL, et al. Among authors: hur js. Cell Rep. 2014 Nov 20;9(4):1228-34. doi: 10.1016/j.celrep.2014.10.031. Epub 2014 Nov 20. Cell Rep. 2014. PMID: 25456125 Free PMC article.
Analysis of 1,25-Dihydroxyvitamin D3 Genomic Action Reveals Calcium-Regulating and Calcium-Independent Effects in Mouse Intestine and Human Enteroids.
Li S, De La Cruz J, Hutchens S, Mukhopadhyay S, Criss ZK, Aita R, Pellon-Cardenas O, Hur J, Soteropoulos P, Husain S, Dhawan P, Verlinden L, Carmeliet G, Fleet JC, Shroyer NF, Verzi MP, Christakos S. Li S, et al. Among authors: hur j. Mol Cell Biol. 2020 Dec 21;41(1):e00372-20. doi: 10.1128/MCB.00372-20. Print 2020 Dec 21. Mol Cell Biol. 2020. PMID: 33139494 Free PMC article.