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Small molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers.
Sci Rep. 2021 May 27;11(1):11185. doi: 10.1038/s41598-021-90801-7.
Sci Rep. 2021.
PMID: 34045646
Free PMC article.
Quantitative Map of β-Lactone-Induced Virulence Regulation.
Krysiak J, Stahl M, Vomacka J, Fetzer C, Lakemeyer M, Fux A, Sieber SA.
Krysiak J, et al. Among authors: fux a.
J Proteome Res. 2017 Mar 3;16(3):1180-1192. doi: 10.1021/acs.jproteome.6b00705. Epub 2017 Feb 10.
J Proteome Res. 2017.
PMID: 28186774
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Biochemical and Proteomic Studies of Human Pyridoxal 5'-Phosphate-Binding Protein (PLPBP).
Fux A, Sieber SA.
Fux A, et al.
ACS Chem Biol. 2020 Jan 17;15(1):254-261. doi: 10.1021/acschembio.9b00857. Epub 2019 Dec 26.
ACS Chem Biol. 2020.
PMID: 31825581
Free PMC article.
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Customizing Functionalized Cofactor Mimics to Study the Human Pyridoxal 5'-Phosphate-Binding Proteome.
Fux A, Pfanzelt M, Kirsch VC, Hoegl A, Sieber SA.
Fux A, et al.
Cell Chem Biol. 2019 Oct 17;26(10):1461-1468.e7. doi: 10.1016/j.chembiol.2019.08.003. Epub 2019 Aug 22.
Cell Chem Biol. 2019.
PMID: 31447350
Free PMC article.
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A comprehensive set of ER protein disulfide isomerase family members supports the biogenesis of proinflammatory interleukin 12 family cytokines.
Mideksa YG, Aschenbrenner I, Fux A, Kaylani D, Weiß CAM, Nguyen TA, Bach NC, Lang K, Sieber SA, Feige MJ.
Mideksa YG, et al. Among authors: fux a.
J Biol Chem. 2022 Dec;298(12):102677. doi: 10.1016/j.jbc.2022.102677. Epub 2022 Nov 4.
J Biol Chem. 2022.
PMID: 36336075
Free PMC article.
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Chemical Cross-Linking Enables Drafting ClpXP Proximity Maps and Taking Snapshots of In Situ Interaction Networks.
Fux A, Korotkov VS, Schneider M, Antes I, Sieber SA.
Fux A, et al.
Cell Chem Biol. 2019 Jan 17;26(1):48-59.e7. doi: 10.1016/j.chembiol.2018.10.007. Epub 2018 Nov 8.
Cell Chem Biol. 2019.
PMID: 30415967
Free article.
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