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Small molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers.
Sci Rep. 2021 May 27;11(1):11185. doi: 10.1038/s41598-021-90801-7.
Sci Rep. 2021.
PMID: 34045646
Free PMC article.
Inhibition of Cdk5 induces cell death of tumor-initiating cells.
Mandl MM, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar AM, Liebl J.
Mandl MM, et al.
Br J Cancer. 2017 Mar 28;116(7):912-922. doi: 10.1038/bjc.2017.39. Epub 2017 Feb 21.
Br J Cancer. 2017.
PMID: 28222068
Free PMC article.
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Design and synthesis of tailored human caseinolytic protease P inhibitors.
Gronauer TF , Mandl MM , Lakemeyer M , Hackl MW , Meßner M , Korotkov VS , Pachmayr J , Sieber SA .
Gronauer TF , et al. Among authors: mandl mm.
Chem Commun (Camb). 2018 Aug 28;54(70):9833-9836. doi: 10.1039/c8cc05265d.
Chem Commun (Camb). 2018.
PMID: 30109319
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