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Page 1
3D chromatin remodeling potentiates transcriptional programs driving cell invasion.
Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2203452119. doi: 10.1073/pnas.2203452119. Epub 2022 Aug 29.
Proc Natl Acad Sci U S A. 2022.
PMID: 36037342
Free PMC article.
Beyond EZH2: is the polycomb protein CBX2 an emerging target for anti-cancer therapy?
Jangal M, Lebeau B, Witcher M.
Jangal M, et al. Among authors: lebeau b.
Expert Opin Ther Targets. 2019 Jul;23(7):565-578. doi: 10.1080/14728222.2019.1627329. Epub 2019 Jun 10.
Expert Opin Ther Targets. 2019.
PMID: 31177918
Review.
Item in Clipboard
STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer.
Totten SP, Im YK, Cepeda Cañedo E, Najyb O, Nguyen A, Hébert S, Ahn R, Lewis K, Lebeau B, La Selva R, Sabourin V, Martínez C, Savage P, Kuasne H, Avizonis D, Santos Martínez N, Chabot C, Aguilar-Mahecha A, Goulet ML, Dankner M, Witcher M, Petrecca K, Basik M, Pollak M, Topisirovic I, Lin R, Siegel PM, Kleinman CL, Park M, St-Pierre J, Ursini-Siegel J.
Totten SP, et al. Among authors: lebeau b.
Nat Commun. 2021 Jun 3;12(1):3299. doi: 10.1038/s41467-021-23396-2.
Nat Commun. 2021.
PMID: 34083537
Free PMC article.
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MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors.
Kim H, Lebeau B, Papadopoli D, Jovanovic P, Russo M, Avizonis D, Morita M, Afzali F, Ursini-Siegel J, Postovit LM, Witcher M, Topisirovic I.
Kim H, et al. Among authors: lebeau b.
iScience. 2024 Feb 12;27(3):109188. doi: 10.1016/j.isci.2024.109188. eCollection 2024 Mar 15.
iScience. 2024.
PMID: 38433910
Free PMC article.
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POGZ promotes homology-directed DNA repair in an HP1-dependent manner.
Heath J, Cheyou ES, Findlay S, Luo VM, Carpio EP, Lee J, Djerir B, Chen X, Morin T, Lebeau B, Karam M, Bagci H, Grapton D, Ursini-Siegel J, Côté JF, Witcher M, Richard S, Maréchal A, Orthwein A.
Heath J, et al. Among authors: lebeau b.
EMBO Rep. 2022 Jan 5;23(1):e51041. doi: 10.15252/embr.202051041. Epub 2021 Nov 10.
EMBO Rep. 2022.
PMID: 34758190
Free PMC article.
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Single base-pair resolution analysis of DNA binding motif with MoMotif reveals an oncogenic function of CTCF zinc-finger 1 mutation.
Lebeau B, Zhao K, Jangal M, Zhao T, Guerra M, Greenwood CMT, Witcher M.
Lebeau B, et al.
Nucleic Acids Res. 2022 Aug 26;50(15):8441-8458. doi: 10.1093/nar/gkac658.
Nucleic Acids Res. 2022.
PMID: 35947648
Free PMC article.
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