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Year Number of Results
2005 2
2010 2
2015 2
2017 1
2019 1
2020 2
2021 2
2022 3
2023 3
2024 0

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18 results

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Page 1
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
Zatreanu D, Robinson HMR, Alkhatib O, Boursier M, Finch H, Geo L, Grande D, Grinkevich V, Heald RA, Langdon S, Majithiya J, McWhirter C, Martin NMB, Moore S, Neves J, Rajendra E, Ranzani M, Schaedler T, Stockley M, Wiggins K, Brough R, Sridhar S, Gulati A, Shao N, Badder LM, Novo D, Knight EG, Marlow R, Haider S, Callen E, Hewitt G, Schimmel J, Prevo R, Alli C, Ferdinand A, Bell C, Blencowe P, Bot C, Calder M, Charles M, Curry J, Ekwuru T, Ewings K, Krajewski W, MacDonald E, McCarron H, Pang L, Pedder C, Rigoreau L, Swarbrick M, Wheatley E, Willis S, Wong AC, Nussenzweig A, Tijsterman M, Tutt A, Boulton SJ, Higgins GS, Pettitt SJ, Smith GCM, Lord CJ. Zatreanu D, et al. Among authors: charles m. Nat Commun. 2021 Jun 17;12(1):3636. doi: 10.1038/s41467-021-23463-8. Nat Commun. 2021. PMID: 34140467 Free PMC article.
Identifying strategies to target the metabolic flexibility of tumours.
Méndez-Lucas A, Lin W, Driscoll PC, Legrave N, Novellasdemunt L, Xie C, Charles M, Wilson Z, Jones NP, Rayport S, Rodríguez-Justo M, Li V, MacRae JI, Hay N, Chen X, Yuneva M. Méndez-Lucas A, et al. Among authors: charles m. Nat Metab. 2020 Apr;2(4):335-350. doi: 10.1038/s42255-020-0195-8. Epub 2020 Apr 21. Nat Metab. 2020. PMID: 32694609 Free PMC article.
Cytokine Storm and Mucus Hypersecretion in COVID-19: Review of Mechanisms.
Khan MA, Khan ZA, Charles M, Pratap P, Naeem A, Siddiqui Z, Naqvi N, Srivastava S. Khan MA, et al. Among authors: charles m. J Inflamm Res. 2021 Jan 22;14:175-189. doi: 10.2147/JIR.S271292. eCollection 2021. J Inflamm Res. 2021. PMID: 33519225 Free PMC article. Review.
Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.
Stockley ML, Ferdinand A, Benedetti G, Blencowe P, Boyd SM, Calder M, Charles MD, Edwardes LV, Ekwuru T, Finch H, Galbiati A, Geo L, Grande D, Grinkevich V, Holliday ND, Krajewski WW, MacDonald E, Majithiya JB, McCarron H, McWhirter CL, Patel V, Pedder C, Rajendra E, Ranzani M, Rigoreau LJM, Robinson HMR, Schaedler T, Sirina J, Smith GCM, Swarbrick ME, Turnbull AP, Willis S, Heald RA. Stockley ML, et al. Among authors: charles md. J Med Chem. 2022 Oct 27;65(20):13879-13891. doi: 10.1021/acs.jmedchem.2c01142. Epub 2022 Oct 6. J Med Chem. 2022. PMID: 36200480
Establishing the selective phospholipid membrane coordination, permeation and lysis properties for a series of 'druggable' supramolecular self-associating antimicrobial amphiphiles.
Boles JE, Bennett C, Baker J, Hilton KLF, Kotak HA, Clark ER, Long Y, White LJ, Lai HY, Hind CK, Sutton JM, Garrett MD, Cheasty A, Ortega-Roldan JL, Charles M, Haynes CJE, Hiscock JR. Boles JE, et al. Among authors: charles m. Chem Sci. 2022 Aug 10;13(33):9761-9773. doi: 10.1039/d2sc02630a. eCollection 2022 Aug 24. Chem Sci. 2022. PMID: 36091903 Free PMC article.
Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication.
Guedán A, Swieboda D, Charles M, Toussaint M, Johnston SL, Asfor A, Panjwani A, Tuthill TJ, Danahay H, Raynham T, Mousnier A, Solari R. Guedán A, et al. Among authors: charles m. J Virol. 2017 Apr 13;91(9):e00217-17. doi: 10.1128/JVI.00217-17. Print 2017 May 1. J Virol. 2017. PMID: 28228588 Free PMC article.
18 results