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2007 1
2011 2
2012 3
2013 2
2016 2
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2020 3
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22 results

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Page 1
CRISPR Screening Identifies Mechanisms of Resistance to KRASG12C and SHP2 Inhibitor Combinations in Non-Small Cell Lung Cancer.
Prahallad A, Weiss A, Voshol H, Kerr G, Sprouffske K, Yuan T, Ruddy D, Meistertzheim M, Kazic-Legueux M, Kottarathil T, Piquet M, Cao Y, Martinuzzi-Duboc L, Buhles A, Adler F, Mannino S, Tordella L, Sansregret L, Maira SM, Graus Porta D, Fedele C, Brachmann SM. Prahallad A, et al. Among authors: sprouffske k. Cancer Res. 2023 Dec 15;83(24):4130-4141. doi: 10.1158/0008-5472.CAN-23-1127. Cancer Res. 2023. PMID: 37934115 Free PMC article.
Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens.
Barbosa IAM, Gopalakrishnan R, Mercan S, Mourikis TP, Martin T, Wengert S, Sheng C, Ji F, Lopes R, Knehr J, Altorfer M, Lindeman A, Russ C, Naumann U, Golji J, Sprouffske K, Barys L, Tordella L, Schübeler D, Schmelzle T, Galli GG. Barbosa IAM, et al. Among authors: sprouffske k. Nat Commun. 2023 Jul 3;14(1):3907. doi: 10.1038/s41467-023-39527-w. Nat Commun. 2023. PMID: 37400441 Free PMC article.
Cancer in light of experimental evolution.
Sprouffske K, Merlo LM, Gerrish PJ, Maley CC, Sniegowski PD. Sprouffske K, et al. Curr Biol. 2012 Sep 11;22(17):R762-71. doi: 10.1016/j.cub.2012.06.065. Curr Biol. 2012. PMID: 22975007 Free PMC article. Review.
Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance.
Cotton JL, Estrada Diez J, Sagar V, Chen J, Piquet M, Alford J, Song Y, Li X, Riester M, DiMare MT, Schumacher K, Boulay G, Sprouffske K, Fan L, Burks T, Mansur L, Wagner J, Bhang HC, Iartchouk O, Reece-Hoyes J, Morris EJ, Hammerman PS, Ruddy DA, Korn JM, Engelman JA, Niederst MJ. Cotton JL, et al. Among authors: sprouffske k. Cancer Res. 2023 Nov 1;83(21):3611-3623. doi: 10.1158/0008-5472.CAN-23-0144. Cancer Res. 2023. PMID: 37603596
Application of simultaneous selective pressures slows adaptation.
Merlo LMF, Sprouffske K, Howard TC, Gardiner KL, Caulin AF, Blum SM, Evans P, Bedalov A, Sniegowski PD, Maley CC. Merlo LMF, et al. Among authors: sprouffske k. Evol Appl. 2020 Aug 15;13(7):1615-1625. doi: 10.1111/eva.13062. eCollection 2020 Aug. Evol Appl. 2020. PMID: 32952608 Free PMC article.
Protein destabilization underlies pathogenic missense mutations in ARID1B.
Mermet-Meillon F, Mercan S, Bauer-Probst B, Allard C, Bleu M, Calkins K, Knehr J, Altorfer M, Naumann U, Sprouffske K, Barys L, Sesterhenn F, Galli GG. Mermet-Meillon F, et al. Among authors: sprouffske k. Nat Struct Mol Biol. 2024 Feb 12. doi: 10.1038/s41594-024-01229-2. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38347147
Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens.
Lopes R, Sprouffske K, Sheng C, Uijttewaal ECH, Wesdorp AE, Dahinden J, Wengert S, Diaz-Miyar J, Yildiz U, Bleu M, Apfel V, Mermet-Meillon F, Krese R, Eder M, Olsen AV, Hoppe P, Knehr J, Carbone W, Cuttat R, Waldt A, Altorfer M, Naumann U, Weischenfeldt J, deWeck A, Kauffmann A, Roma G, Schübeler D, Galli GG. Lopes R, et al. Among authors: sprouffske k. Sci Adv. 2021 Jul 2;7(27):eabf5733. doi: 10.1126/sciadv.abf5733. Print 2021 Jul. Sci Adv. 2021. PMID: 34215580 Free PMC article.
Exquisite Sensitivity to Dual BRG1/BRM ATPase Inhibitors Reveals Broad SWI/SNF Dependencies in Acute Myeloid Leukemia.
Rago F, Rodrigues LU, Bonney M, Sprouffske K, Kurth E, Elliott G, Ambrose J, Aspesi P, Oborski J, Chen JT, McDonald ER, Mapa FA, Ruddy DA, Kauffmann A, Abrams T, Bhang HC, Jagani Z. Rago F, et al. Among authors: sprouffske k. Mol Cancer Res. 2022 Mar 1;20(3):361-372. doi: 10.1158/1541-7786.MCR-21-0390. Mol Cancer Res. 2022. PMID: 34799403
22 results