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2024 | 2 |
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Page 1
Feedback, Crosstalk and Competition: Ingredients for Emergent Non-Linear Behaviour in the PI3K/mTOR Signalling Network.
Int J Mol Sci. 2021 Jun 28;22(13):6944. doi: 10.3390/ijms22136944.
Int J Mol Sci. 2021.
PMID: 34203293
Free PMC article.
Review.
Dynamic modelling of the PI3K/MTOR signalling network uncovers biphasic dependence of mTORC1 activity on the mTORC2 subunit SIN1.
Ghomlaghi M, Yang G, Shin SY, James DE, Nguyen LK.
Ghomlaghi M, et al.
PLoS Comput Biol. 2021 Sep 16;17(9):e1008513. doi: 10.1371/journal.pcbi.1008513. eCollection 2021 Sep.
PLoS Comput Biol. 2021.
PMID: 34529665
Free PMC article.
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Development and validation of 'Patient Optimizer' (POP) algorithms for predicting surgical risk with machine learning.
Kowadlo G, Mittelberg Y, Ghomlaghi M, Stiglitz DK, Kishore K, Guha R, Nazareth J, Weinberg L.
Kowadlo G, et al. Among authors: ghomlaghi m.
BMC Med Inform Decis Mak. 2024 Mar 11;24(1):70. doi: 10.1186/s12911-024-02463-w.
BMC Med Inform Decis Mak. 2024.
PMID: 38468330
Free PMC article.
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Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis.
Kearney AL, Norris DM, Ghomlaghi M, Kin Lok Wong M, Humphrey SJ, Carroll L, Yang G, Cooke KC, Yang P, Geddes TA, Shin S, Fazakerley DJ, Nguyen LK, James DE, Burchfield JG.
Kearney AL, et al. Among authors: ghomlaghi m.
Elife. 2021 Jul 13;10:e66942. doi: 10.7554/eLife.66942.
Elife. 2021.
PMID: 34253290
Free PMC article.
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Integrative modeling and analysis of signaling crosstalk reveal molecular switches coordinating Yes-associated protein transcriptional activities.
Ghomlaghi M, Theocharous M, Hoang N, Shin SY, von Kriegsheim A, O' Neill E, Zhang T, Nguyen LK.
Ghomlaghi M, et al.
iScience. 2024 Jan 26;27(3):109031. doi: 10.1016/j.isci.2024.109031. eCollection 2024 Mar 15.
iScience. 2024.
PMID: 38380257
Free PMC article.
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