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Cholesterol is required for transcriptional repression by BASP1.
Loats AE, Carrera S, Fleming AF, Roberts ARE, Sherrard A, Toska E, Moorhouse AJ, Medler KF, Roberts SGE. Loats AE, et al. Among authors: sherrard a. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2101671118. doi: 10.1073/pnas.2101671118. Proc Natl Acad Sci U S A. 2021. PMID: 34266955 Free PMC article.
A transient pool of nuclear F-actin at mitotic exit controls chromatin organization.
Baarlink C, Plessner M, Sherrard A, Morita K, Misu S, Virant D, Kleinschnitz EM, Harniman R, Alibhai D, Baumeister S, Miyamoto K, Endesfelder U, Kaidi A, Grosse R. Baarlink C, et al. Among authors: sherrard a. Nat Cell Biol. 2017 Dec;19(12):1389-1399. doi: 10.1038/ncb3641. Epub 2017 Nov 13. Nat Cell Biol. 2017. PMID: 29131140
The small molecule inhibitor YK-4-279 disrupts mitotic progression of neuroblastoma cells, overcomes drug resistance and synergizes with inhibitors of mitosis.
Kollareddy M, Sherrard A, Park JH, Szemes M, Gallacher K, Melegh Z, Oltean S, Michaelis M, Cinatl J Jr, Kaidi A, Malik K. Kollareddy M, et al. Among authors: sherrard a. Cancer Lett. 2017 Sep 10;403:74-85. doi: 10.1016/j.canlet.2017.05.027. Epub 2017 Jun 7. Cancer Lett. 2017. PMID: 28602975 Free PMC article.